Intraparenchymal Hyperattenuations on Flat-Panel CT Directly After Mechanical Thrombectomy are Restricted to the Initial Infarct Core on Diffusion-Weighted Imaging.
Schneider T, Mahraun T, Schroeder J, Froelich A, Hölter P, Wagner M, Darcourt J, Cognard C, Bonafe A, Fiehler J, Siemonsen S, Buhk JH (2018)
Publication Type: Journal article
Publication year: 2018
Journal
Book Volume: 28
Pages Range: 91-97
Journal Issue: 1
DOI: 10.1007/s00062-016-0543-y
Abstract
PURPOSE: The presence of intraparenchymal hyperattenuations (IPH) on flat-panel computed tomography (FP-CT) after endovascular recanalization in stroke patients is a common phenomenon. They are thought to occur in ischemic areas with breakdown of the blood-brain barrier but previous studies that investigated a mutual interaction are scarce. We aimed to assess the relationship of IPH localization with prethrombectomy diffusion-weighted imaging (DWI) lesions. METHODS: This retrospective multicenter study included 27 acute stroke patients who underwent DWI prior to FP-CT following mechanical thrombectomy. After software-based coregistration of DWI and FP-CT, lesion volumetry was conducted and overlapping was analyzed. RESULTS: Two different patterns were observed: IPH corresponding to the DWI lesion and IPH exceeding the DWI lesion. The latter showed demarcated infarction of DWI exceeding IPH at 24 h. No major hemorrhage following IPH was observed. Most IPH were manifested within the basal ganglia and insular cortex. CONCLUSION: The IPH primarily appeared within the initial ischemic core and secondarily within the penumbral tissue that progressed to infarction. The IPH represent the minimum final infarct volume, which may help in periinterventional decision making.
Authors with CRIS profile
Involved external institutions
Universitätsklinikum Hamburg-Eppendorf (UKE)
Germany (DE)
Universitätsklinikum Frankfurt am Main (KGU)
Germany (DE)
Hôpital Purpan - Centre Hospitalier Universitaire (CHU) de Toulouse
France (FR)
Hôpital Saint Eloi
France (FR)
Germany (DE)
Universitätsklinikum Frankfurt am Main (KGU)
Germany (DE)
Hôpital Purpan - Centre Hospitalier Universitaire (CHU) de Toulouse
France (FR)
Hôpital Saint Eloi
France (FR)
How to cite
APA:
Schneider, T., Mahraun, T., Schroeder, J., Froelich, A., Hölter, P., Wagner, M.,... Buhk, J.-H. (2018). Intraparenchymal Hyperattenuations on Flat-Panel CT Directly After Mechanical Thrombectomy are Restricted to the Initial Infarct Core on Diffusion-Weighted Imaging. Clinical Neuroradiology, 28(1), 91-97. https://doi.org/10.1007/s00062-016-0543-y
MLA:
Schneider, Tanja, et al. "Intraparenchymal Hyperattenuations on Flat-Panel CT Directly After Mechanical Thrombectomy are Restricted to the Initial Infarct Core on Diffusion-Weighted Imaging." Clinical Neuroradiology 28.1 (2018): 91-97.
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