Double cross-linked supramolecular hydrogels with tunable properties based on host-guest interactions

Che Y, Gaitzsch J, Liubimtsev N, Zschoche S, Bauer T, Appelhans D, Voit B (2020)

Publication Type: Journal article

Publication year: 2020

Journal

Soft Matter Royal Society of Chemistry

Book Volume: 16

Pages Range: 6733-6742

Journal Issue: 29

DOI: 10.1039/d0sm00833h

Abstract

We report a novel double cross-linked hydrogel system based on polyacrylamide and poly(2-methyl-2-oxazoline) (PMOXA) network chains, as well as on supramolecular host-guest interactions with on-demand tailored mechanical properties. Well-defined vinyl-bearing PMOXA macromonomers, functionalized with either β-cyclodextrin units (β-CD-PMOXA) or adamantane units (Ada-PMOXA), were synthesized and confirmed using 1H NMR, MALDI-TOF-MS and GPC measurements. The complexation between adamantane and β-CD modified macromonomers in solution towards bismacromonomers was confirmed by 2D NOESY NMR and DLS. After introducing these bismacromonomers into the polyacrylamide hydrogel, the supramolecular non-covalent Ada/β-CD bond was responsible for the presence of PMOXA network chains to form a dense network. Once the interactions broke, the PMOXA chains no longer contributed to the network, but became dangling graft side chains in a predominated polyacrylamide network. Their dissociative nature influenced the physical properties, including the swelling behavior and mechanics of the final hydrogel. Rheological experiments proved that the E-modulus of the network was significantly increased by the supramolecular host-guest interactions. Tuning the lengths of PMOXA network chains even allowed the modification of the changes in mechanical strength, also through the addition of free β-CD. The tunable properties of the double cross-linked supramolecular hydrogel proved their unique strength for future applications. This journal is

Involved external institutions

Leibniz-Institut für Polymerforschung Dresden e. V. DE Germany (DE) Technische Universität Dresden DE Germany (DE)

How to cite

APA:

Che, Y., Gaitzsch, J., Liubimtsev, N., Zschoche, S., Bauer, T., Appelhans, D., & Voit, B. (2020). Double cross-linked supramolecular hydrogels with tunable properties based on host-guest interactions. Soft Matter, 16(29), 6733-6742. https://doi.org/10.1039/d0sm00833h

MLA:

Che, Yunjiao, et al. "Double cross-linked supramolecular hydrogels with tunable properties based on host-guest interactions." Soft Matter 16.29 (2020): 6733-6742.

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