Mechanically Defined Microgels by Droplet Microfluidics
Heida T, Neubauer JW, Seuss M, Hauck N, Thiele J, Fery A (2017)
Publication Type: Journal article
Publication year: 2017
Journal
Book Volume: 218
Article Number: 1600418
Journal Issue: 2
Abstract
Over the last two decades, droplet-based microfluidics has evolved into a versatile tool for fabricating tailored micrometer-sized hydrogel particles. Combining precise fluid handling down to femtoliter scale with diverse hydrogel precursor design, it allows for excellent control over microgel size and shape, but also functionalization and crosslinking density. Consequently, it is possible to tune physicochemical and mechanical properties such as swelling, degradation, stimuli sensitivity, and elasticity by microfluidic droplet templates. This has led to a recent trend in applying microgels as experimental platform in cell culturing, drug delivery, sensing, and tissue engineering. This article highlights advances in microfluidic droplet formation as templates for microgels with tailored physicochemical properties. Special focus is put on evolving design strategies for the synthesis of mechanically defined microgels, their applications, and methods for mechanical characterization on single-particle level. (Figure presented.).
Involved external institutions
Germany (DE)How to cite
APA:
Heida, T., Neubauer, J.W., Seuss, M., Hauck, N., Thiele, J., & Fery, A. (2017). Mechanically Defined Microgels by Droplet Microfluidics. Macromolecular Chemistry and Physics, 218(2). https://doi.org/10.1002/macp.201600418
MLA:
Heida, Thomas, et al. "Mechanically Defined Microgels by Droplet Microfluidics." Macromolecular Chemistry and Physics 218.2 (2017).
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