Ultrasensitive detection of Ebola matrix protein in a memristor mode

Ibarlucea B, Akbar TF, Kim K, Rim T, Baek CK, Ascoli A, Tetzlaff R, Baraban L, Cuniberti G (2018)

Publication Type: Journal article

Publication year: 2018

Journal

Nano Research

Book Volume: 11

Pages Range: 1057-1068

Journal Issue: 2

DOI: 10.1007/s12274-017-1720-2

Abstract

We demonstrate the direct biosensing of the Ebola VP40 matrix protein, using a memristor mode of a liquid-integrated nanodevice, based on a large array of honeycomb-shaped silicon nanowires. To shed more light on the principle of biodetection using memristors, we engineered the opening of the current-minima voltage gap VGAP by involving the third gap-control electrode (gate voltage, VG) into the system. The primary role of VG is to mimic the presence of the charged species of the desired sign at the active area of the sensor. We further showed the advantages of biodetection with an initially opened controlled gap (VGAP ≠ 0), which allows the detection of the lowest concentrations of the biomolecules carrying arbitrary positive or negative charges; this feature was not present in previous configurations. We compared the bio-memristor performance, in terms of its detection range and sensitivity, to that of the already-known field-effect transistor (FET) mode by operating the same device. To our knowledge, this is the first demonstration of Ebola matrix protein detection using a nanoscaled electrical sensor.

Involved external institutions

Technische Universität Dresden DE Germany (DE) Pohang University of Science and Technology (POSTECH) KR Korea, Republic of (KR)

How to cite

APA:

Ibarlucea, B., Akbar, T.F., Kim, K., Rim, T., Baek, C.-K., Ascoli, A.,... Cuniberti, G. (2018). Ultrasensitive detection of Ebola matrix protein in a memristor mode. Nano Research, 11(2), 1057-1068. https://doi.org/10.1007/s12274-017-1720-2

MLA:

Ibarlucea, Bergoi, et al. "Ultrasensitive detection of Ebola matrix protein in a memristor mode." Nano Research 11.2 (2018): 1057-1068.

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