Patch test results with the European baseline series and additions thereof in the ESSCA network, 2015-2018

Uter W, Bauer A, Belloni Fortina A, Bircher AJ, Brans R, Buhl T, Cooper SM, Czarnecka-Operacz M, Dickel H, Dugonik A, Geier J, Gimenez-Arnau AM, Goncalo M, Johansen JD, Johnston GA, Mahler V, Rustemeyer T, Sanchez-Perez J, Schuttelaar MLA, Simon D, Spiewak R, Valiukeviciene S, Weisshaar E, White IR, Wilkinson M (2020)

Publication Type: Journal article

Publication year: 2020

Journal

DOI: 10.1111/cod.13704

Abstract

Background Clinical surveillance of the prevalence of contact allergy in consecutively patch tested patients is a proven instrument to continually assess the importance of contact allergens (haptens) assembled in a baseline series. Objectives To present current results from the European Surveillance System on Contact Allergies, including 13 countries represented by 1 to 11 departments. Methods Anonymized or pseudonymized patch test and clinical data from various data capture systems used locally or nationally as transferred to the Erlangen data centre were pooled and descriptively analysed after quality control. Results In the 4 years (2015-2018), data from 51 914 patients patch tested with the European baseline series (EBS) of contact allergens were analysed. Contact allergy to nickel was most frequent (17.6% positive), followed by contact allergy to fragrance mix I (6.9%), methylisothiazolinone (MI; 6.2%), andMyroxylon pereiraeresin (balsam of Peru; 5.8%). Conclusions While the prevalence of MI contact allergy decreased substantially following regulatory intervention, the persistently high levels of allergy to metals, fragrances, other preservatives, and rubber chemicals point to problems needing further research and, potentially, preventive efforts. Results with national additions to the baseline series provide important information on substances possibly to be considered for inclusion in the EBS.

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Involved external institutions

Oxford University Hospitals NHS Foundation Trust United Kingdom (GB) University of Padua / Universita degli Studi di Padova Italy (IT) Guy's and St Thomas' (NHS Foundation Trust) United Kingdom (GB) University of Groningen / Rijksuniversiteit Groningen Netherlands (NL) Universitätsklinikum Heidelberg Germany (DE) Lithuanian University of Health Sciences / Lietuvos sveikatos mokslų universitetas (LSMU) Lithuania (LT) Jagiellonian University / Uniwersytet Jagielloński (UJ) Poland (PL) Leeds Teaching Hospitals NHS Trust United Kingdom (GB) Universität Bern Switzerland (CH) Vrije Universiteit Amsterdam (VU) / University Amsterdam Netherlands (NL) Hospital Universitario De La Princesa Spain (ES) Universitätsspital Basel Switzerland (CH) Universidade de Coimbra Portugal (PT) Universitätsklinikum Göttingen Germany (DE) Technische Universität Dresden Germany (DE) Universitat Pompeu Fabra (UPF) Spain (ES) University of Leicester United Kingdom (GB) Poznan University of Medical Sciences / Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu Poland (PL) Maribor University Medical Centre (Maribor UMC) / Univerzitetni klinični center Maribor Slovenia (SI) Universität Osnabrück Germany (DE) Ruhr-Universität Bochum (RUB) Germany (DE) Gentofte Hospital Denmark (DK)

How to cite

APA:

Uter, W., Bauer, A., Belloni Fortina, A., Bircher, A.J., Brans, R., Buhl, T.,... Wilkinson, M. (2020). Patch test results with the European baseline series and additions thereof in the ESSCA network, 2015-2018. Contact Dermatitis. https://doi.org/10.1111/cod.13704

MLA:

Uter, Wolfgang, et al. "Patch test results with the European baseline series and additions thereof in the ESSCA network, 2015-2018." Contact Dermatitis (2020).

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