Human S-cone electroretinograms obtained by silent substitution stimulation

Maguire J, Parry NRA, Kremers J, Murray IJ, Mckeefry D (2018)


Publication Status: Published

Publication Type: Journal article

Publication year: 2018

Journal

Publisher: OPTICAL SOC AMER

Book Volume: 35

Pages Range: B11-B18

Journal Issue: 4

DOI: 10.1364/JOSAA.35.000B11

Abstract

We used triple silent substitution stimuli to characterize human S-cone electroretinograms (ERGs) in normal trichromats. Short-wavelength-cone (S-cone) ERGs were found to have different morphological features and temporal frequency response characteristics compared to ERGs derived from L-cones, M-cones, and rod photoreceptors in normal participants. Furthermore, in two cases of retinal pathology, blue cone monochromatism (BCM) and enhanced S-cone syndrome (ESCS), S-cone ERGs elicited by our stimuli were preserved and enhanced, respectively. The results from both normal and pathological retinae demonstrate that triple silent substitution stimuli can be used to generate ERGs that provide an assay of human S-cone function. (c) 2018 Optical Society of America

Authors with CRIS profile

Involved external institutions

How to cite

APA:

Maguire, J., Parry, N.R.A., Kremers, J., Murray, I.J., & Mckeefry, D. (2018). Human S-cone electroretinograms obtained by silent substitution stimulation. Journal of the Optical Society of America A-Optics Image Science and Vision, 35(4), B11-B18. https://dx.doi.org/10.1364/JOSAA.35.000B11

MLA:

Maguire, J., et al. "Human S-cone electroretinograms obtained by silent substitution stimulation." Journal of the Optical Society of America A-Optics Image Science and Vision 35.4 (2018): B11-B18.

BibTeX: Download