Setting up a collaborative European human biological monitoring study on occupational exposure to hexavalent chromium

Journal article


Publication Details

Author(s): Santonen T, Alimonti A, Bocca B, Duca RC, Galea KS, Godderis L, Göen T, Gomes B, Hanser O, Iavicoli I, Janasik B, Jones K, Kiilunen M, Koch HM, Leese E, Leso V, Louro H, Ndaw S, Porras SP, Robert A, Ruggieri F, Scheepers PT, Silva MJ, Viegas S, Wasowicz W, Castano A, Sepai O
Journal: Environmental Research
Publication year: 2019
ISSN: 0013-9351


Abstract

The EU human biomonitoring initiative, HBM4EU, aims to co-ordinate and advance human biomonitoring (HBM) across Europe. Within its remit, the project is gathering new, policy relevant, EU-wide data on occupational exposure to relevant priority chemicals and developing new approaches for occupational biomonitoring. In this manuscript, the hexavalent chromium [Cr(VI)] study design is presented as the first example of this HBM4EU approach. This study involves eight European countries and plans to recruit 400 workers performing Cr(VI) surface treatment e.g. electroplating or stainless steel welding activities. The aim is to collect new data on current occupational exposure to Cr(VI) in Europe and to test new methods for Cr biomonitoring, specifically the analysis of Cr(VI) in exhaled breath condensate (EBC) and Cr in red blood cells (RBC) in addition to traditional urinary total Cr analyses. Furthermore, exposure data will be complemented with early biological effects data, including genetic and epigenetic effects. Personal air samples and wipe samples are collected in parallel to help informing the biomonitoring results. We present standard operational procedures (SOPs) to support the harmonized methodologies for the collection of occupational hygiene and HBM samples in different countries.


FAU Authors / FAU Editors

Göen, Thomas Prof. Dr.
Lehrstuhl für Arbeits- und Sozialmedizin


External institutions with authors

Finnish Institute of Occupational Health (FIOH) / Työterveyslaitos (TTL)
HSE Health and Safety Executive
INRS Institut National de Recherche et Sécurité
Instituto de Salud Carlos III (Institute of Health Carlos III, ISCIII)
IOM Institute of Occupational Medicine
Istituto Superiore di Sanità (ISS)
Katholieke Universiteit Leuven (KUL) / Catholic University of Leuven
Nofer Institute of Occupational Medicine (NIOM)
Public Health England (PHE)
Radboud Institute for Health Sciences
Ruhr-Universität Bochum (RUB)
Universidade Nova de Lisboa
Università degli Studi di Napoli Federico II


How to cite

APA:
Santonen, T., Alimonti, A., Bocca, B., Duca, R.C., Galea, K.S., Godderis, L.,... Sepai, O. (2019). Setting up a collaborative European human biological monitoring study on occupational exposure to hexavalent chromium. Environmental Research. https://dx.doi.org/10.1016/j.envres.2019.108583

MLA:
Santonen, T., et al. "Setting up a collaborative European human biological monitoring study on occupational exposure to hexavalent chromium." Environmental Research (2019).

BibTeX: 

Last updated on 2019-05-08 at 07:23