Management of supine hypertension in patients with neurogenic orthostatic hypotension: scientific statement of the American Autonomic Society, European Federation of Autonomic Societies, and the European Society of Hypertension

Jordan J, Fanciulli A, Tank J, Calandra-Buonaura G, Cheshire WP, Cortelli P, Eschlboeck S, Grassi G, Hilz MJ, Kaufmann H, Lahrmann H, Mancia G, Mayer G, Norcliffe-Kaufmann L, Pavy-Le Traon A, Raj SR, Robertson D, Rocha I, Reuter H, Struhal W, Thijs RD, Tsioufis KP, Gert van Dijk J, Wenning GK, Biaggioni I (2019)

Publication Type: Journal article

Publication year: 2019

Journal

Book Volume: 37

Pages Range: 1541-1546

Journal Issue: 8

DOI: 10.1097/HJH.0000000000002078

Abstract

: Supine hypertension commonly occurs in patients with neurogenic orthostatic hypotension due to autonomic failure. Supine hypertension promotes nocturnal sodium excretion and orthostatic hypotension, thus, interfering with quality of life. Perusal of the literature on essential hypertension and smaller scale investigations in autonomic failure patients also suggest that supine hypertension may predispose to cardiovascular and renal disease. These reasons provide a rationale for treating supine hypertension. Yet, treatment of supine hypertension, be it through nonpharmacological or pharmacological approaches, may exacerbate orthostatic hypotension when patients get up during the night. Fall-related complications may occur. More research is needed to define the magnitude of the deleterious effects of supine hypertension on cardiovascular, cerebrovascular, and renal morbidity and mortality. Integration of more precise cardiovascular risk assessment, efficacy, and safety data, and the prognosis of the underlying condition causing autonomic failure is required for individualized management recommendations.

Authors with CRIS profile

Involved external institutions

Leiden University Medical Center Netherlands (NL) National and Kapodistrian University of Athens Greece (GR) Stichting Epilepsie Instellingen Nederland (SEIN) Netherlands (NL) Vanderbilt University United States (USA) (US) Medizinische Universität Innsbruck Austria (AT) Mayo Clinic Hospital United States (USA) (US) Karl Landsteiner Privatuniversität für Gesundheitswissenschaften GmbH Austria (AT) Deutsches Zentrum für Luft- und Raumfahrt e.V. (DLR) / German Aerospace Center Germany (DE) Centro di Fisiologia Clinica e Ipertensione Italy (IT) University of Lisbon / Universidade de Lisboa (ULisboa) Portugal (PT) University of Bologna / Università di Bologna Italy (IT) New York University (NYU) United States (USA) (US) University of Calgary Canada (CA) Universität zu Köln Germany (DE) Centre Hospitalier Universitaire (CHU) de Toulouse France (FR) University of Milano-Bicocca / Università degli Studi di Milano-Bicocca, UNIMIB Italy (IT)

How to cite

APA:

Jordan, J., Fanciulli, A., Tank, J., Calandra-Buonaura, G., Cheshire, W.P., Cortelli, P.,... Biaggioni, I. (2019). Management of supine hypertension in patients with neurogenic orthostatic hypotension: scientific statement of the American Autonomic Society, European Federation of Autonomic Societies, and the European Society of Hypertension. Journal of Hypertension, 37(8), 1541-1546. https://dx.doi.org/10.1097/HJH.0000000000002078

MLA:

Jordan, Jens, et al. "Management of supine hypertension in patients with neurogenic orthostatic hypotension: scientific statement of the American Autonomic Society, European Federation of Autonomic Societies, and the European Society of Hypertension." Journal of Hypertension 37.8 (2019): 1541-1546.

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