Towards in-vivo X-ray nanoscopy: The effect of motion on image quality

Beitrag bei einer Tagung
(Konferenzbeitrag)


Details zur Publikation

Autorinnen und Autoren: Mill L, Bier B, Syben C, Kling L, Grüneboom A, Christiansen S, Schett G, Maier A
Herausgeber: Thomas M. Deserno, Andreas Maier, Christoph Palm, Heinz Handels, Klaus H. Maier-Hein, Thomas Tolxdorff
Verlag: Springer Berlin Heidelberg
Jahr der Veröffentlichung: 2018
Tagungsband: Informatik aktuell
Seitenbereich: 115-120
Sprache: Englisch


Abstract

Novel X-Ray Microscopy (XRM) systems allow to study the internal structure of a specimen on nanoscale. A possible use of this non-destructive technology is motivated in the medical research area. In-Vivo investigation of medication over a period of time and its effects on perfusion and bony structure might lead to a better understanding of drug mechanisms and diseases like Osteoporosis and could lead to new approaches to their treatment. The first step towards in-vivo XRM imaging is to investigate the suitability of recent XRM systems for this task and subsequently to determine the system parameters. In this context, the impact of mice motion on the image quality is studied in this work. This paper aims to simulate the effects of breathing motion and muscle relaxation of the mice on the reconstructed images, which already effects the projection images. We therefore assume a mouse’s respiration motion pattern, which happens four time during a single projection acquisitions, and the muscle relaxation movement due to anesthesia and simulate its impacts on image quality. Additionally, we show that a frame rate of at least 16 fps is needed to capture in-vivo movements in order to apply state-of-the-art motion correction methods.


FAU-Autorinnen und Autoren / FAU-Herausgeberinnen und Herausgeber

Bier, Bastian
Lehrstuhl für Informatik 5 (Mustererkennung)
Maier, Andreas Prof. Dr.-Ing.
Lehrstuhl für Informatik 5 (Mustererkennung)
Mill, Leonid
Lehrstuhl für Informatik 5 (Mustererkennung)
Schett, Georg Prof. Dr. med.
Lehrstuhl für Innere Medizin III
Syben, Christopher
Lehrstuhl für Informatik 5 (Mustererkennung)


Einrichtungen weiterer Autorinnen und Autoren

Freie Universität Berlin
Helmholtz-Zentrum Berlin für Materialien und Energie (HZB)


Zitierweisen

APA:
Mill, L., Bier, B., Syben, C., Kling, L., Grüneboom, A., Christiansen, S.,... Maier, A. (2018). Towards in-vivo X-ray nanoscopy: The effect of motion on image quality. In Thomas M. Deserno, Andreas Maier, Christoph Palm, Heinz Handels, Klaus H. Maier-Hein, Thomas Tolxdorff (Eds.), Informatik aktuell (pp. 115-120). Erlangen, DE: Springer Berlin Heidelberg.

MLA:
Mill, Leonid, et al. "Towards in-vivo X-ray nanoscopy: The effect of motion on image quality." Proceedings of the Workshop on Bildverarbeitung fur die Medizin, 2018, Erlangen Ed. Thomas M. Deserno, Andreas Maier, Christoph Palm, Heinz Handels, Klaus H. Maier-Hein, Thomas Tolxdorff, Springer Berlin Heidelberg, 2018. 115-120.

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Zuletzt aktualisiert 2019-24-07 um 12:46