Two decades of SPECT/CT – the coming of age of a technology: An updated review of literature evidence

Journal article
(Review article)


Publication Details

Author(s): Israel O, Pellet O, Biassoni L, De Palma D, Estrada-Lobato E, Gnanasegaran G, Kuwert T, la Fougère C, Mariani G, Massalha S, Paez D, Giammarile F
Journal: European Journal of Nuclear Medicine and Molecular Imaging
Publication year: 2019
ISSN: 1619-7070


Abstract

Purpose: Single-photon emission computed tomography (SPECT) combined with computed tomography (CT) was introduced as a hybrid SPECT/CT imaging modality two decades ago. The main advantage of SPECT/CT is the increased specificity achieved through a more precise localization and characterization of functional findings. The improved diagnostic accuracy is also associated with greater diagnostic confidence and better inter-specialty communication. Methods: This review presents a critical assessment of the relevant literature published so far on the role of SPECT/CT in a variety of clinical conditions. It also includes an update on the established evidence demonstrating both the advantages and limitations of this modality. Conclusions: For the majority of applications, SPECT/CT should be a routine imaging technique, fully integrated into the clinical decision-making process, including oncology, endocrinology, orthopaedics, paediatrics, and cardiology. Large-scale prospective studies are lacking, however, on the use of SPECT/CT in certain clinical domains such as neurology and lung disorders. The review also presents data on the complementary role of SPECT/CT with other imaging modalities and a comparative analysis, where available.


FAU Authors / FAU Editors

Kuwert, Torsten Prof. Dr.
Lehrstuhl für Klinische Nuklearmedizin


External institutions with authors

ASST dei Sette Laghi
International Atomic Energy Agency (IAEA)
Leeds Teaching Hospitals NHS Trust
Technion - Israel Institute of Technology
Universitätsklinikum Tübingen
University College London (UCL)
University of Ottawa
University of Pisa / Università di Pisa (UniPi)


How to cite

APA:
Israel, O., Pellet, O., Biassoni, L., De Palma, D., Estrada-Lobato, E., Gnanasegaran, G.,... Giammarile, F. (2019). Two decades of SPECT/CT – the coming of age of a technology: An updated review of literature evidence. European Journal of Nuclear Medicine and Molecular Imaging. https://dx.doi.org/10.1007/s00259-019-04404-6

MLA:
Israel, Ora, et al. "Two decades of SPECT/CT – the coming of age of a technology: An updated review of literature evidence." European Journal of Nuclear Medicine and Molecular Imaging (2019).

BibTeX: 

Last updated on 2019-23-07 at 01:08