Exploration of new contrasts, targets, and MR imaging and spectroscopy techniques for neuromuscular disease-A workshop report of working group 3 of the biomedicine and molecular biosciences COST action BM1304 MYO-MRI

Journal article
(Review article)


Publication Details

Author(s): Strijkers GJ, Araujo EC, Azzabou N, Bendahan D, Blamire A, Burakiewicz J, Carlier PG, Damon B, Deligianni X, Froeling M, Heerschap A, Hollingsworth KG, Hooijmans MT, Karampinos DC, Loudos G, Madelin G, Marty B, Nagel AM, Nederveen AJ, Nelissen JL, Santini F, Scheidegger O, Schick F, Sinclair C, Sinkus R, De Sousa PL, Straub V, Walter G, Kan HE
Journal: Journal of Neuromuscular Diseases
Publication year: 2019
Volume: 6
Journal issue: 1
Pages range: 1-30
ISSN: 2214-3602


Abstract

Neuromuscular diseases are characterized by progressive muscle degeneration and muscle weakness resulting in functional disabilities. While each of these diseases is individually rare, they are common as a group, and a large majority lacks effective treatment with fully market approved drugs. Magnetic resonance imaging and spectroscopy techniques (MRI and MRS) are showing increasing promise as an outcome measure in clinical trials for these diseases. In 2013, the European Union funded the COST (co-operation in science and technology) action BM1304 called MYO-MRI (www.myo-mri.eu), with the overall aim to advance novel MRI and MRS techniques for both diagnosis and quantitative monitoring of neuromuscular diseases through sharing of expertise and data, joint development of protocols, opportunities for young researchers and creation of an online atlas of muscle MRI and MRS. In this report, the topics that were discussed in the framework of working group 3, which had the objective to: Explore new contrasts, new targets and new imaging techniques for NMD are described. The report is written by the scientists who attended the meetings and presented their data. An overview is given on the different contrasts that MRI can generate and their application, clinical needs and desired readouts, and emerging methods.


FAU Authors / FAU Editors

Nagel, Armin Michael Prof. Dr.
Professur für metabolische und funktionelle MR-Bildgebung


External institutions with authors

Aix-Marseille University / Aix-Marseille Université
BioEmission Technology Solutions
Eberhard Karls Universität Tübingen
French Alternative Energies and Atomic Energy Commission (CEA)
Inselspital, Universitätsspital Bern
King’s College London
Leiden University Medical Center
Newcastle University
New York University (NYU)
Radboud University Nijmegen Medical Centre / Radboudumc of voluit Radboud Universitair Medisch Centrum (UMC)
Technische Universität München (TUM)
UCL Institute of Neurology
Universitätsspital Basel
Université de Strasbourg (UDS)
University Medical Centre Utrecht (UMC Utrecht)
University of Amsterdam
University of Florida
Vanderbilt University


How to cite

APA:
Strijkers, G.J., Araujo, E.C., Azzabou, N., Bendahan, D., Blamire, A., Burakiewicz, J.,... Kan, H.E. (2019). Exploration of new contrasts, targets, and MR imaging and spectroscopy techniques for neuromuscular disease-A workshop report of working group 3 of the biomedicine and molecular biosciences COST action BM1304 MYO-MRI. Journal of Neuromuscular Diseases, 6(1), 1-30. https://dx.doi.org/10.3233/JND-180333

MLA:
Strijkers, Gustav J., et al. "Exploration of new contrasts, targets, and MR imaging and spectroscopy techniques for neuromuscular disease-A workshop report of working group 3 of the biomedicine and molecular biosciences COST action BM1304 MYO-MRI." Journal of Neuromuscular Diseases 6.1 (2019): 1-30.

BibTeX: 

Last updated on 2019-16-07 at 08:38