Saake M, Seuß H, Hammon M, Ellmann S, May M, Uder M, Schmid A (2019)
Publication Type: Journal article
Publication year: 2019
Background: Liver dynamic computed tomography (CT) is an established method for pre- and post-interventional evaluation of hepatocellular carcinoma. To date only the liver parenchyma and perfusion information of dynamic CT has been evaluated widely. Purpose: To evaluate the vascular information contained in dynamic CT datasets. Material and Methods: Dynamic CT performed one day after transarterial chemoembolization (60 mL of contrast medium, 6 mL/s, 40 s scan duration) were retrospectively evaluated. Conventional slice and angiographic maximum-intensity-projection reconstructions were calculated on a multi-modality post-processing platform. Datasets were evaluated for viable tumor, anatomy of the vasculature, and potential tumor-feeding vessels. The results were compared to digital subtraction angiography images. Results: In total, 94 treated hepatocellular carcinoma nodules were evaluated (62 dynamic CT scans, 46 patients [34 men; mean age = 69 years]). Forty-six partially viable tumors were diagnosed after transarterial chemoembolization. In all of these, tumor-feeding vessels were found in dynamic CT. Seventeen suspected extra-hepatic tumor feeders were reported, of which 14 had not been found during previous transarterial chemoembolization. Conclusion: Dynamic CT is useful in post-interventional imaging of hepatocellular carcinoma after transarterial chemoembolization due to its ability to detect residual viable tumor parts and to show previously unknown intra- and extra-hepatic tumor-feeding vessels.
APA:
Saake, M., Seuß, H., Hammon, M., Ellmann, S., May, M., Uder, M., & Schmid, A. (2019). Dynamic CT angiography for therapy evaluation after transarterial chemoembolization of hepatocellular carcinoma. Acta Radiologica. https://dx.doi.org/10.1177/0284185119854601
MLA:
Saake, Marc, et al. "Dynamic CT angiography for therapy evaluation after transarterial chemoembolization of hepatocellular carcinoma." Acta Radiologica (2019).
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