Multinuclear MRI at Ultrahigh Fields

Journal article


Publication Details

Author(s): Niesporek SC, Nagel AM, Platt T
Journal: Topics in Magnetic Resonance Imaging
Publication year: 2019
Volume: 28
Journal issue: 3
Pages range: 173-188
ISSN: 0899-3459
eISSN: 1536-1004


Abstract

In this article, an overview of the current developments and research applications for non-proton magnetic resonance imaging (MRI) at ultrahigh magnetic fields (UHFs) is given. Due to technical and methodical advances, efficient MRI of physiologically relevant nuclei, such as Na, Cl, Cl, K, O, or P has become feasible and is of interest to obtain spatially and temporally resolved information that can be used for biomedical and diagnostic applications. Sodium (Na) MRI is the most widespread multinuclear imaging method with applications ranging over all regions of the human body. Na MRI yields the second largest in vivo NMR signal after the clinically used proton signal (H). However, other nuclei such as O and P (energy metabolism) or Cl and K (cell viability) are used in an increasing number of MRI studies at UHF. One major advancement has been the increased availability of whole-body MR scanners with UHFs (B0 ≥7T) expanding the range of detectable nuclei. Nevertheless, efforts in terms of pulse sequence and post-processing developments as well as hardware designs must be made to obtain valuable information in clinically feasible measurement times. This review summarizes the available methods in the field of non-proton UHF MRI, especially for Na MRI, as well as introduces potential applications in clinical research.


FAU Authors / FAU Editors

Nagel, Armin Michael Prof. Dr.
Professur für metabolische und funktionelle MR-Bildgebung


External institutions with authors

Deutsches Krebsforschungszentrum (DKFZ)


How to cite

APA:
Niesporek, S.C., Nagel, A.M., & Platt, T. (2019). Multinuclear MRI at Ultrahigh Fields. Topics in Magnetic Resonance Imaging, 28(3), 173-188. https://dx.doi.org/10.1097/RMR.0000000000000201

MLA:
Niesporek, Sebastian C., Armin Michael Nagel, and Tanja Platt. "Multinuclear MRI at Ultrahigh Fields." Topics in Magnetic Resonance Imaging 28.3 (2019): 173-188.

BibTeX: 

Last updated on 2019-03-07 at 12:53