Challenges and perspectives in brain tissue testing and modeling

Beitrag in einer Fachzeitschrift
(Originalarbeit)


Details zur Publikation

Autorinnen und Autoren: Budday S, Holzapfel GA, Steinmann P, Kuhl E
Herausgeber: Poceedings in Applied Mathematics and Mechanics
Zeitschrift: Proceedings in Applied Mathematics and Mechanics
Verlag: WILEY-VCH Verlag GmbH & Co. KGaA
Verlagsort: Weinheim
Jahr der Veröffentlichung: 2019
Band: accepted
Tagungsband: accepted
ISSN: 1617-7061


Abstract











While long underestimated, more and more evidence confirms that mechanics play a critical role for brain function and
dysfunction. Therefore, computational simulations based on the field equations of nonlinear continuum mechanics can provide
important insights into the underlying mechanisms of brain injury and disease. Realistic numerical predictions, however,
require models capable of capturing the complex and unique mechanical behavior of this ultrasoft, highly heterogeneous and
adaptive tissue. In recent years, contradictory experimental results have retarded progress in this field. Here, we summarize
the key characteristics of brain tissue behavior on different length and time scales and propose application-specific modeling
approaches, which are as complex as necessary but as simple as possible. The presented considerations will, on the one
hand, facilitate well-designed future experiments and, on the other hand, help to choose the appropriate constitutive law for a
specific application.





FAU-Autorinnen und Autoren / FAU-Herausgeberinnen und Herausgeber

Budday, Silvia Dr.-Ing.
Lehrstuhl für Technische Mechanik
Steinmann, Paul Prof. Dr.-Ing.
Lehrstuhl für Technische Mechanik


Einrichtungen weiterer Autorinnen und Autoren

Stanford University
Technische Universität Graz


Zitierweisen

APA:
Budday, S., Holzapfel, G.A., Steinmann, P., & Kuhl, E. (2019). Challenges and perspectives in brain tissue testing and modeling. Proceedings in Applied Mathematics and Mechanics, accepted.

MLA:
Budday, Silvia, et al. "Challenges and perspectives in brain tissue testing and modeling." Proceedings in Applied Mathematics and Mechanics accepted (2019).

BibTeX: 

Zuletzt aktualisiert 2019-01-07 um 08:53