Targeting mucosal healing in Crohn’s disease: what the clinician needs to know

Journal article
(Review article)


Publication Details

Author(s): Klenske E, Bojarski C, Waldner M, Rath T, Neurath M, Atreya R
Journal: Therapeutic Advances in Gastroenterology
Publication year: 2019
Volume: 12
ISSN: 1756-283X
eISSN: 1756-2848


Abstract

In recent years, mucosal healing has emerged as a key therapeutic goal in the clinical management of patients with Crohn’s disease, as it has been associated with improved long-term clinical outcomes. With the vast improvements in endoscopic imaging techniques and the increase in available treatment options, which reportedly are able to induce mucosal healing, the practising physician is left to wonder: how is endoscopic mucosal healing exactly defined in Crohn’s disease, and how can it effectively be achieved and monitored in daily clinical practice? Within this review, we will give an overview of the ongoing debate about the definition of mucosal healing and the modalities to monitor inflammation, and finally present available therapies with the capacity to induce mucosal healing.


FAU Authors / FAU Editors

Atreya, Raja Prof. Dr.
Juniorprofessur für chronisch entzündliche Darmerkrankungen
Neurath, Markus Prof. Dr.
Lehrstuhl für Innere Medizin I
Rath, Timo Prof. Dr. med.
Medizinische Klinik 1 - Gastroenterologie, Pneumologie und Endokrinologie
Waldner, Maximilian Prof. Dr.
Lehrstuhl für Innere Medizin I


External institutions with authors

Charité - Universitätsmedizin Berlin


How to cite

APA:
Klenske, E., Bojarski, C., Waldner, M., Rath, T., Neurath, M., & Atreya, R. (2019). Targeting mucosal healing in Crohn’s disease: what the clinician needs to know. Therapeutic Advances in Gastroenterology, 12. https://dx.doi.org/10.1177/1756284819856865

MLA:
Klenske, Entcho, et al. "Targeting mucosal healing in Crohn’s disease: what the clinician needs to know." Therapeutic Advances in Gastroenterology 12 (2019).

BibTeX: 

Last updated on 2019-26-06 at 11:08