Targeting mucosal healing in Crohn’s disease: what the clinician needs to know
Klenske E, Bojarski C, Waldner M, Rath T, Neurath M, Atreya R (2019)
Publication Type: Journal article, Review article
Publication year: 2019
Journal
Book Volume: 12
Abstract
In recent years, mucosal healing has emerged as a key therapeutic goal in the clinical management of patients with Crohn’s disease, as it has been associated with improved long-term clinical outcomes. With the vast improvements in endoscopic imaging techniques and the increase in available treatment options, which reportedly are able to induce mucosal healing, the practising physician is left to wonder: how is endoscopic mucosal healing exactly defined in Crohn’s disease, and how can it effectively be achieved and monitored in daily clinical practice? Within this review, we will give an overview of the ongoing debate about the definition of mucosal healing and the modalities to monitor inflammation, and finally present available therapies with the capacity to induce mucosal healing.
Authors with CRIS profile
Maximilian Waldner
Lehrstuhl für Innere Medizin I
Timo Rath
Department of Medicine 1 – Gastroenterology, Pneumology and Endocrinology
Markus Neurath
Lehrstuhl für Innere Medizin I
Raja Atreya
Professur für Translationale Immunforschung bei chronisch entzündlichen Darmerkrankungen (Heisenberg-Professur)
Involved external institutions
Germany (DE)How to cite
APA:
Klenske, E., Bojarski, C., Waldner, M., Rath, T., Neurath, M., & Atreya, R. (2019). Targeting mucosal healing in Crohn’s disease: what the clinician needs to know. Therapeutic Advances in Gastroenterology, 12. https://dx.doi.org/10.1177/1756284819856865
MLA:
Klenske, Entcho, et al. "Targeting mucosal healing in Crohn’s disease: what the clinician needs to know." Therapeutic Advances in Gastroenterology 12 (2019).
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