Proteomics of Bordetella pertussis whole-cell and acellular vaccines

Journal article


Publication Details

Author(s): Möller J, Kraner M, Burkovski A
Journal: BMC Research Notes
Publication year: 2019
Volume: 12
Journal issue: 1
ISSN: 1756-0500


Abstract

Objectives: Bordetella pertussis is the etiological agent of whooping cough, a bacterial infection of especially children, which may be fatal without treatment. In frame of studies to investigate putative effects of vaccination on host-pathogen interaction and clonal distribution of strains, in addition to Corynebacterium diphtheriae and Clostridium tetani toxoid vaccines, also whole-cell and acellular pertussis vaccines were analyzed by mass spectrometry. Data description: LC-MS/MS spectra were generated and analyzed using B. pertussis genome data and proteins present in whole-cell and acellular pertussis vaccines were identified. Subcellular localization of proteins and presence of signal peptides was determined bioinformatically.


FAU Authors / FAU Editors

Burkovski, Andreas Prof. Dr.
Professur für Mikrobiologie
Kraner, Max Dr.
Lehrstuhl für Biochemie
Möller, Jens
Professur für Mikrobiologie


How to cite

APA:
Möller, J., Kraner, M., & Burkovski, A. (2019). Proteomics of Bordetella pertussis whole-cell and acellular vaccines. BMC Research Notes, 12(1). https://dx.doi.org/10.1186/s13104-019-4373-2

MLA:
Möller, Jens, Max Kraner, and Andreas Burkovski. "Proteomics of Bordetella pertussis whole-cell and acellular vaccines." BMC Research Notes 12.1 (2019).

BibTeX: 

Last updated on 2019-24-06 at 08:53