Proteomics of Bordetella pertussis whole-cell and acellular vaccines

Möller J, Kraner M, Burkovski A (2019)


Publication Type: Journal article

Publication year: 2019

Journal

Book Volume: 12

Article Number: 329

Journal Issue: 1

DOI: 10.1186/s13104-019-4373-2

Abstract

Objectives: Bordetella pertussis is the etiological agent of whooping cough, a bacterial infection of especially children, which may be fatal without treatment. In frame of studies to investigate putative effects of vaccination on host-pathogen interaction and clonal distribution of strains, in addition to Corynebacterium diphtheriae and Clostridium tetani toxoid vaccines, also whole-cell and acellular pertussis vaccines were analyzed by mass spectrometry. Data description: LC-MS/MS spectra were generated and analyzed using B. pertussis genome data and proteins present in whole-cell and acellular pertussis vaccines were identified. Subcellular localization of proteins and presence of signal peptides was determined bioinformatically.

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How to cite

APA:

Möller, J., Kraner, M., & Burkovski, A. (2019). Proteomics of Bordetella pertussis whole-cell and acellular vaccines. BMC Research Notes, 12(1). https://dx.doi.org/10.1186/s13104-019-4373-2

MLA:

Möller, Jens, Max Kraner, and Andreas Burkovski. "Proteomics of Bordetella pertussis whole-cell and acellular vaccines." BMC Research Notes 12.1 (2019).

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