Renal Denervation Update From the International Sympathetic Nervous System Summit: JACC State-of-the-Art Review

Journal article
(Review article)


Publication Details

Author(s): Kiuchi MG, Esler MD, Fink GD, Osborn JW, Banek CT, Böhm M, Denton KM, DiBona GF, Everett TH, Grassi G, Katholi RE, Knuepfer MM, Kopp UC, Lefer DJ, Lohmeier TE, May CN, Mahfoud F, Paton JF, Schmieder R, Pellegrino PR, Sharabi Y, Schlaich MP
Journal: Journal of the American College of Cardiology
Publication year: 2019
Volume: 73
Journal issue: 23
Pages range: 3006-3017
ISSN: 0735-1097


Abstract

Three recent renal denervation studies in both drug-naïve and drug-treated hypertensive patients demonstrated a significant reduction of ambulatory blood pressure compared with respective sham control groups. Improved trial design, selection of relevant patient cohorts, and optimized interventional procedures have likely contributed to these positive findings. However, substantial variability in the blood pressure response to renal denervation can still be observed and remains a challenging and important problem. The International Sympathetic Nervous System Summit was convened to bring together experts in both experimental and clinical medicine to discuss the current evidence base, novel developments in our understanding of neural interplay, procedural aspects, monitoring of technical success, and others. Identification of relevant trends in the field and initiation of tailored and combined experimental and clinical research efforts will help to address remaining questions and provide much-needed evidence to guide clinical use of renal denervation for hypertension treatment and other potential indications.


FAU Authors / FAU Editors

Schmieder, Roland Prof. Dr.
Professur für Innere Medizin (Nephrologie)


External institutions with authors

Baker Idi Heart And Diabetes Institute
Indiana University – Purdue University Indianapolis
Louisiana State University Health Sciences Center
Michigan State University
Monash University
Saint Louis University (SLU)
St. John's Hospital
Tel Aviv University
The University of Melbourne
Universitätsklinikum des Saarlandes
University of Auckland
University of Iowa
University of Milano-Bicocca / Università degli Studi di Milano-Bicocca, UNIMIB
University of Minnesota (UMN)
University of Mississippi (Ole Miss)
University of Nebraska Medical Center
University of Western Australia (UWA)


How to cite

APA:
Kiuchi, M.G., Esler, M.D., Fink, G.D., Osborn, J.W., Banek, C.T., Böhm, M.,... Schlaich, M.P. (2019). Renal Denervation Update From the International Sympathetic Nervous System Summit: JACC State-of-the-Art Review. Journal of the American College of Cardiology, 73(23), 3006-3017. https://dx.doi.org/10.1016/j.jacc.2019.04.015

MLA:
Kiuchi, Márcio G., et al. "Renal Denervation Update From the International Sympathetic Nervous System Summit: JACC State-of-the-Art Review." Journal of the American College of Cardiology 73.23 (2019): 3006-3017.

BibTeX: 

Last updated on 2019-16-07 at 08:38