Joint association of mammographic density adjusted for age and body mass index and polygenic risk score with breast cancer risk

Vachon CM, Scott CG, Tamimi RM, Thompson DJ, Fasching P, Stone J, Southey MC, Winham S, Lindstrom S, Lilyquist J, Giles GG, Milne RL, Macinnis RJ, Baglietto L, Li J, Czene K, Bolla MK, Wang Q, Dennis J, Häberle L, Eriksson M, Kraft P, Luben R, Wareham N, Olson JE, Norman A, Polley EC, Maskarinec G, Le Marchand L, Haiman CA, Hopper JL, Couch FJ, Easton DF, Hall P, Chatterjee N, Garcia-Closas M (2019)


Publication Type: Journal article

Publication year: 2019

Journal

Book Volume: 21

DOI: 10.1186/s13058-019-1138-8

Abstract

Background: Mammographic breast density, adjusted for age and body mass index, and a polygenic risk score (PRS), comprised of common genetic variation, are both strong risk factors for breast cancer and increase discrimination of risk models. Understanding their joint contribution will be important to more accurately predict risk.

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How to cite

APA:

Vachon, C.M., Scott, C.G., Tamimi, R.M., Thompson, D.J., Fasching, P., Stone, J.,... Garcia-Closas, M. (2019). Joint association of mammographic density adjusted for age and body mass index and polygenic risk score with breast cancer risk. Breast Cancer Research, 21. https://dx.doi.org/10.1186/s13058-019-1138-8

MLA:

Vachon, Celine M., et al. "Joint association of mammographic density adjusted for age and body mass index and polygenic risk score with breast cancer risk." Breast Cancer Research 21 (2019).

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