Quality of life and disease severity in dermatitis patients with fragrance allergy—A cross-sectional European questionnaire study
Bennike NH, Heisterberg MS, White IR, Mahler V, Silvestre-Salvador JF, Giménez-Arnau A, Johansen JD (2019)
Publication Type: Journal article
Publication year: 2019
Journal
DOI: 10.1111/cod.13252
Abstract
Background: Fragrance contact allergy is common, but few studies on quality of life (QoL) in affected patients exist. Recently, the disease-specific Fragrance Quality of Life Index (FQLI) was developed. Objectives: To characterize QoL in European dermatitis patients with fragrance contact allergy at the time of diagnosis. Methods: This was a cross-sectional study, in which 2011 Danish, British, Spanish and German adult consecutive dermatitis patients were invited to complete a questionnaire on self-reported disease severity, the Dermatology Life Quality Index (DLQI), and the FQLI immediately prior to being patch tested. Results: One thousand seven hundred and fifty-eight patients responded, and 259 (14.7%; country range 11.7%-18.5%) were fragrance-positive. Among these, the total (SD) DLQI score was 6.2 (5.6) and the total (SD) FQLI score was 60 (25), with both estimates being comparable to those in fragrance-negative patients. Adjusting the total FQLI score for age, sex and self-rated disease severity showed a higher (ie, worse) score in fragrance-positive patients (3.6-point increase; 95% confidence interval: 0.30-6.8 points; P = 0.03). Specifically, contact allergy to oxidized linalool was associated with greater impairment in QoL. Conclusions: QoL in patients with fragrance contact allergy is impaired at a level comparable to that in other patch tested dermatitis patients, at the time of diagnosis, across several European countries.
Authors with CRIS profile
Additional Organisation(s)
Involved external institutions
Copenhagen University Hospital
Denmark (DK)
Guy's and St Thomas' (NHS Foundation Trust)
United Kingdom (GB)
Autonomous University of Barcelona (UAB) / Universitat Autònoma de Barcelona
Spain (ES)
Hospital General Universitario de Alicante
Spain (ES)
Denmark (DK)
Guy's and St Thomas' (NHS Foundation Trust)
United Kingdom (GB)
Autonomous University of Barcelona (UAB) / Universitat Autònoma de Barcelona
Spain (ES)
Hospital General Universitario de Alicante
Spain (ES)
How to cite
APA:
Bennike, N.H., Heisterberg, M.S., White, I.R., Mahler, V., Silvestre-Salvador, J.F., Giménez-Arnau, A., & Johansen, J.D. (2019). Quality of life and disease severity in dermatitis patients with fragrance allergy—A cross-sectional European questionnaire study. Contact Dermatitis. https://dx.doi.org/10.1111/cod.13252
MLA:
Bennike, Niels H., et al. "Quality of life and disease severity in dermatitis patients with fragrance allergy—A cross-sectional European questionnaire study." Contact Dermatitis (2019).
BibTeX: Download