Chronic hand eczema in Germany: 5-year follow-up data from the CARPE registry

Journal article


Publication Details

Author(s): Apfelbacher CJ, Ofenloch RF, Weisshaar E, Molin S, Bauer A, Mahler V, Heinrich A, Von Kiedrowski R, Schmitt J, Elsner P, Diepgen TL
Journal: Contact Dermatitis
Publication year: 2019
Volume: 80
Journal issue: 1
Pages range: 45-53
ISSN: 0105-1873


Abstract

Background: The CARPE registry was set up in 2009 to prospectively investigate the management of patients with chronic hand eczema (CHE). Objectives: To report comprehensive follow-up data from the CARPE registry. Patients and methods: We investigated sociodemographic and clinical characteristics, provision of medical care, physician-assessed outcomes, and patient-reported outcomes (PROs). Data were collected between 2009 and 2016, with up to 5 years of follow-up, and are reported descriptively. Results: Overall, 1281 patients were included in the registry (53.7% female). Mean age was 47.0 years. Of the patients, 793 and 231 completed the 2-year follow-up and 5-year follow-up, respectively. At baseline, 5.4% had changed or given up their job because of CHE, the average duration of CHE was 6.1 years, and, in 22.4%, the CHE was severe according to physician global assessment. Systemic treatment (alitretinoin, acitretin, and methotrexate) was prescribed at least once to 39.0% of the patients during the course of the follow-up. Disease severity, quality of life and treatment satisfaction improved over time, and the proportion of patients receiving systemic treatments decreased. Conclusions: Under continued dermatological care, substantial improvements in disease severity and PROs over time was achieved during the course of the CARPE registry, even in patients with long-standing and severe hand eczema.


FAU Authors / FAU Editors

Mahler, Vera Prof. Dr.
Medizinische Fakultät


Additional Organisation
Hautklinik


External institutions with authors

Co-med GmbH & Co.KG
Ludwig-Maximilians-Universität (LMU)
Ruprecht-Karls-Universität Heidelberg
Technische Universität Dresden
Universität Regensburg
Universitätsklinikum Jena


How to cite

APA:
Apfelbacher, C.J., Ofenloch, R.F., Weisshaar, E., Molin, S., Bauer, A., Mahler, V.,... Diepgen, T.L. (2019). Chronic hand eczema in Germany: 5-year follow-up data from the CARPE registry. Contact Dermatitis, 80(1), 45-53. https://dx.doi.org/10.1111/cod.13113

MLA:
Apfelbacher, Christian J., et al. "Chronic hand eczema in Germany: 5-year follow-up data from the CARPE registry." Contact Dermatitis 80.1 (2019): 45-53.

BibTeX: 

Last updated on 2019-27-05 at 13:53