Electronic Effects on Chiral NHC-Transition-Metal Catalysis
Yong X, Thurston R, Ho CY (2019)
Publication Type: Journal article, Review article
Publication year: 2019
Journal
Book Volume: 51
Pages Range: 2058-2080
Journal Issue: 10
Abstract
Though the properties of N-heterocyclic carbenes (NHCs) are generally dominated by the very strong σ donating character, electronic activation has emerged as an effective method to cooperate with typical carbon-framework steric optimization for highly enantioselective chiral NHC-transition-metal catalysis in recent years. NHC electronic changes associated with structural variations are now better understood by quantitative analysis using various methods. Here we highlighted and correlated some interesting chiral induction improvement methods, which were brought by electronic and steric cooperation on chiral NHC-transition-metal catalysis. 1 Introduction 2 Hemilabile Sidechains on NHC Ligands 3 Electronic and Bond Angle Changes Brought by NHC Core Size Variations 4 Electronic Activators on the NHC Core 5 Conjugated Systems and Fused Ring Structures 6 Remote Electronic Activators on the N -Aryl Ring 7 Summary and Outlook.
Additional Organisation(s)
Involved external institutions
China (CN)How to cite
APA:
Yong, X., Thurston, R., & Ho, C.Y. (2019). Electronic Effects on Chiral NHC-Transition-Metal Catalysis. Synthesis (Germany), 51(10), 2058-2080. https://dx.doi.org/10.1055/s-0037-1611751
MLA:
Yong, Xuefeng, Ryan Thurston, and Chun Yu Ho. "Electronic Effects on Chiral NHC-Transition-Metal Catalysis." Synthesis (Germany) 51.10 (2019): 2058-2080.
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