Novel approach for the assessment of ovarian follicles infiltration in polymeric electrospun patterned scaffolds

Journal article


Publication Details

Author(s): Raffel N, Dittrich R, Bäuerle T, Seyler L, Amir F, Hoffmann I, Leal-Egaña A, Beckmann M, Boccaccini AR, Liverani L
Journal: PLoS ONE
Publication year: 2019
Volume: 14
Journal issue: 4
ISSN: 1932-6203


Abstract

Reproductive tissue engineering (REPROTEN) has been recently defined as the application of the tissue engineering approach targeting reproductive organs and several research works are focusing on this novel strategy. Being still an innovative field, most of the scaffold characterization techniques suitable for other tissue targets give inappropriate results, and there is the need to evaluate and investigate novel approaches. In particular the focus of this paper is the evaluation of the infiltration of ovarian follicles inside patterned electrospun scaffolds. Beyond the standard techniques, for the first time the use of magnetic resonance imaging (MRI) for this purpose is proposed and specific protocols for scaffold preparation are reported. Positive results in terms of evaluation of scaffolds incorporating follicles confirm this technique as highly effective for further applications in this field.


FAU Authors / FAU Editors

Amir, Fattahi
Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)
Bäuerle, Tobias Prof. Dr.
Professur für Multimodale Bildgebung in der präklinischen Forschung
Beckmann, Matthias Prof. Dr.
Lehrstuhl für Geburtshilfe und Frauenheilkunde
Boccaccini, Aldo R. Prof. Dr.-Ing.
Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)
Dittrich, Ralf Prof. Dr.
Professur für Experimentelle Reproduktionsmedizin
Liverani, Liliana Dr.
Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)
Raffel, Nathalie
Frauenklinik


How to cite

APA:
Raffel, N., Dittrich, R., Bäuerle, T., Seyler, L., Amir, F., Hoffmann, I.,... Liverani, L. (2019). Novel approach for the assessment of ovarian follicles infiltration in polymeric electrospun patterned scaffolds. PLoS ONE, 14(4). https://dx.doi.org/10.1371/journal.pone.0215985

MLA:
Raffel, Nathalie, et al. "Novel approach for the assessment of ovarian follicles infiltration in polymeric electrospun patterned scaffolds." PLoS ONE 14.4 (2019).

BibTeX: 

Last updated on 2019-23-05 at 16:53