Critique of the 2017 epileptic seizure and epilepsy classifications

Lüders H, Akamatsu N, Amina S, Baumgartner C, Benbadis S, Bermeo-Ovalle A, Bleasel A, Bozorgi A, Carreño M, Devereaux M, Fernandez-Baca Vaca G, Francione S, García Losarcos N, Hamer H, Holthausen H, Jamal Omidi S, Kalamangalam G, Kanner A, Knake S, Lacuey N, Lhatoo S, Lim SH, Mani J, Matsumoto R, Miller J, Noachtar S, Palmini A, Park J, Rosenow F, Shahid A, Schuele S, Steinhoff B, Szabo CÁ, Tandon N, Terada K, Van Emde Boas W, Widdess-Walsh P, Kahane P (2019)

Publication Type: Journal article

Publication year: 2019

Journal

DOI: 10.1111/epi.14699

Abstract

This article critiques the International League Against Epilepsy (ILAE) 2015-2017 classifications of epilepsy, epileptic seizures, and status epilepticus. It points out the following shortcomings of the ILAE classifications: (1) they mix semiological terms with epileptogenic zone terminology; (2) simple and widely accepted terminology has been replaced by complex terminology containing less information; (3) seizure evolution cannot be described in any detail; (4) in the four-level epilepsy classification, level two (epilepsy category) overlaps almost 100% with diagnostic level one (seizure type); and (5) the design of different classifications with distinct frameworks for newborns, adults, and patients in status epilepticus is confusing. The authors stress the importance of validating the new ILAE classifications and feel that the decision of Epilepsia to accept only manuscripts that use the ILAE classifications is premature and regrettable.

Authors with CRIS profile

Involved external institutions

Universitätsklinikum Gießen und Marburg (UKGM) Germany (DE) University Hospitals of Cleveland / Case Western Reserve University Hospital United States (USA) (US) University of Florida United States (USA) (US) International University of Health and Welfare (IUHW) / 国際医療福祉大学 Japan (JP) Rush University United States (USA) (US) University of South Florida (USF) United States (USA) (US) Vienna General Hospital / Allgemeines Krankenhaus der Stadt Wien (AKH) Austria (AT) University of Sydney (USYD) Australia (AU) Hospital Clínic de Barcelona Spain (ES) Ospedale Niguarda Ca' Granda / ASST Grande Ospedale Metropolitano Niguarda Italy (IT) University of Miami United States (USA) (US) National Neuroscience Institute (NNI) Singapore (SG) Kokilaben Dhirubhai Ambani Hospital India (IN) Kyoto University Hospital / 京都大学医学部附属病院 Japan (JP) Ludwig-Maximilians-Universität (LMU) Germany (DE) Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) Brazil (BR) University of Grenoble Alpes (UGA) / Université de Grenoble France (FR) Universitätsklinikum Frankfurt am Main (KGU) Germany (DE) Epilepsiezentrum Kork Germany (DE) Northwestern University United States (USA) (US) Foundation Epilepsy Institutes Netherlands Netherlands (NL) Shizuoka Institute of Epilepsy and Neurological Disorders Japan (JP) Beaumont Hospital Ireland (IE) Memorial Hermann United States (USA) (US) UT Health San Antonio United States (USA) (US)

How to cite

APA:

Lüders, H., Akamatsu, N., Amina, S., Baumgartner, C., Benbadis, S., Bermeo-Ovalle, A.,... Kahane, P. (2019). Critique of the 2017 epileptic seizure and epilepsy classifications. Epilepsia. https://dx.doi.org/10.1111/epi.14699

MLA:

Lüders, Hans, et al. "Critique of the 2017 epileptic seizure and epilepsy classifications." Epilepsia (2019).

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