Prevention of Cervical Cancer

Journal article
(Review article)

Publication Details

Author(s): Hillemanns P, Friese K, Dannecker C, Klug S, Seifert U, Iftner T, Haedicke J, Loening T, Horn L, Schmidt D, Ikenberg H, Steiner M, Freitag U, Siebert U, Sroczynski G, Sauerbrei W, Beckmann M, Gebhardt M, Friedrich M, Munstedt K, Schneider A, Kaufmann A, Petry KU, Schaefer APA, Pawlita M, Weis J, Mehnert A, Fehr M, Grimm C, Reich O, Arbyn M, Kleijnen J, Wesselmann S, Nothacker M, Follmann M, Langer T, Jentschke M
Journal: Geburtshilfe und Frauenheilkunde
Publication year: 2019
Volume: 79
Journal issue: 2
Pages range: 160-175
ISSN: 0016-5751


Aims Annual opportunistic screening for cervical carcinoma has been done in Germany since 1971. The creation of this S3 guideline meets an important need, outlined in the National Cancer Plan, with regard to screening for cervical cancer, as this guideline aims to provide important information and support for planned organized screening for cervical cancer in Germany. Methods With the financial support of German Cancer Aid, 21 professional societies developed evidence-based statements and recommendations (classified using the GRADE system) for the screening, management and treatment of precancerous conditions of the cervix. Two independent scientific institutes compiled systematic reviews for this guideline. Recommendations The second part of this short summary deals with the triage, treatment and follow-up care of cervical dysplasia. With regard to those women who do not participate in screening, the guideline authors recommend sending out repeat invitation letters or an HPV self-collection kit. Colposcopy should be carried out for further investigation if cytology findings are Pap II-p and HPV test results are positive or if the results of an HPV 16 or HPV 18 screening test are positive. A single abnormal Pap smear should be triaged and investigated using HPV testing or p16/Ki67 dual staining.

FAU Authors / FAU Editors

Beckmann, Matthias Prof. Dr.
Lehrstuhl für Geburtshilfe und Frauenheilkunde

External institutions with authors

AWMF-Institut für Medizinisches Wissensmanagement (AWMF-IMWi)
Charité - Universitätsmedizin Berlin
Deutsche Krebsgesellschaft (DKG)
Deutsches Krebsforschungszentrum (DKFZ)
HELIOS Kliniken
Kleijnen Systematic Reviews
Klinik Bad Trissl
Klinikum der Universität München
Klinikum Wolfsburg
Medizinische Hochschule Hannover (MHH) / Hannover Medical School
MVZ für Zytologie und Molekularbiologie Frankfurt GbR (CytoMol)
Ortenau Klinikum
Privatklinik Graz Ragnitz
Spital Thurgau AG
Technische Universität Dresden
Technische Universität München (TUM)
UMIT - Private Universität für Gesundheitswissenschaften, Medizinische Informatik und Technik GmbH
Universitätsklinikum Freiburg
Universitätsklinikum Leipzig
Universitätsklinikum Tübingen

How to cite

Hillemanns, P., Friese, K., Dannecker, C., Klug, S., Seifert, U., Iftner, T.,... Jentschke, M. (2019). Prevention of Cervical Cancer. Geburtshilfe und Frauenheilkunde, 79(2), 160-175.

Hillemanns, Peter, et al. "Prevention of Cervical Cancer." Geburtshilfe und Frauenheilkunde 79.2 (2019): 160-175.


Last updated on 2019-14-05 at 09:08