Prevention of Cervical Cancer

Hillemanns P, Friese K, Dannecker C, Klug S, Seifert U, Iftner T, Haedicke J, Loening T, Horn L, Schmidt D, Ikenberg H, Steiner M, Freitag U, Siebert U, Sroczynski G, Sauerbrei W, Beckmann M, Gebhardt M, Friedrich M, Munstedt K, Schneider A, Kaufmann A, Petry KU, Schaefer APA, Pawlita M, Weis J, Mehnert A, Fehr M, Grimm C, Reich O, Arbyn M, Kleijnen J, Wesselmann S, Nothacker M, Follmann M, Langer T, Jentschke M (2019)

Publication Type: Journal article, Review article

Publication year: 2019

Journal

Book Volume: 79

Pages Range: 160-175

Journal Issue: 2

DOI: 10.1055/a-0828-7722

Abstract

Aims Annual opportunistic screening for cervical carcinoma has been done in Germany since 1971. The creation of this S3 guideline meets an important need, outlined in the National Cancer Plan, with regard to screening for cervical cancer, as this guideline aims to provide important information and support for planned organized screening for cervical cancer in Germany. Methods With the financial support of German Cancer Aid, 21 professional societies developed evidence-based statements and recommendations (classified using the GRADE system) for the screening, management and treatment of precancerous conditions of the cervix. Two independent scientific institutes compiled systematic reviews for this guideline. Recommendations The second part of this short summary deals with the triage, treatment and follow-up care of cervical dysplasia. With regard to those women who do not participate in screening, the guideline authors recommend sending out repeat invitation letters or an HPV self-collection kit. Colposcopy should be carried out for further investigation if cytology findings are Pap II-p and HPV test results are positive or if the results of an HPV 16 or HPV 18 screening test are positive. A single abnormal Pap smear should be triaged and investigated using HPV testing or p16/Ki67 dual staining.

Authors with CRIS profile

Involved external institutions

Medizinische Hochschule Hannover (MHH) / Hannover Medical School Germany (DE) Klinik Bad Trissl Germany (DE) Universitätsklinikum Tübingen Germany (DE) Technische Universität Dresden Germany (DE) Klinikum der Universität München Germany (DE) MVZ für Zytologie und Molekularbiologie Frankfurt GbR (CytoMol) Germany (DE) Albertinen-Krankenhaus Germany (DE) Universitätsklinikum Leipzig Germany (DE) Technische Universität München (TUM) Germany (DE) HELIOS Kliniken Germany (DE) Klinikum Wolfsburg Germany (DE) Deutsche Krebsgesellschaft (DKG) Germany (DE) Kleijnen Systematic Reviews United Kingdom (GB) AWMF-Institut für Medizinisches Wissensmanagement (AWMF-IMWi) Germany (DE) Ortenau Klinikum Germany (DE) UMIT - Private Universität für Gesundheitswissenschaften, Medizinische Informatik und Technik GmbH Austria (AT) Universitätsklinikum Freiburg Germany (DE) Deutsches Krebsforschungszentrum (DKFZ) Germany (DE) Spital Thurgau AG Switzerland (CH) Charité - Universitätsmedizin Berlin Germany (DE) Sciensano Belgium (BE) Privatklinik Graz Ragnitz Austria (AT)

How to cite

APA:

Hillemanns, P., Friese, K., Dannecker, C., Klug, S., Seifert, U., Iftner, T.,... Jentschke, M. (2019). Prevention of Cervical Cancer. Geburtshilfe und Frauenheilkunde, 79(2), 160-175. https://dx.doi.org/10.1055/a-0828-7722

MLA:

Hillemanns, Peter, et al. "Prevention of Cervical Cancer." Geburtshilfe und Frauenheilkunde 79.2 (2019): 160-175.

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