Genomic analysis of a novel nontoxigenic Corynebacterium diphtheriae strain isolated from a cancer patient

Journal article


Publication Details

Author(s): Ramdhan ND, Blom J, Sutcliffe IC, Pereira-Ribeiro PM, Santos CS, Mattos-Guaraldi AL, Burkovski A, Sangal V
Journal: New Microbes and New Infections
Publication year: 2019
Volume: 30
ISSN: 2052-2975


Abstract

The genome of a novel nontoxigenic Corynebacterium diphtheriae, strain 5015, isolated from a patient with adenoid cystic carcinoma was sequenced and compared with 117 publically available genomes. This strain is phylogenetically distinct and lacks virulence genes encoding the toxin, BigA and Sdr-like adhesins. Strain 5015 possesses spaD-type and spaH-type pilus gene clusters with a loss of some gene functions, and 31 unique genes that need molecular characterization to understand their potential role in virulence characteristics.


FAU Authors / FAU Editors

Burkovski, Andreas Prof. Dr.
Professur für Mikrobiologie


External institutions with authors

Kerckhoff-Klinik
Northumbria University
Rio de Janeiro State University / Universidade do Estado do Rio de Janeiro (UERJ)


How to cite

APA:
Ramdhan, N.D., Blom, J., Sutcliffe, I.C., Pereira-Ribeiro, P.M., Santos, C.S., Mattos-Guaraldi, A.L.,... Sangal, V. (2019). Genomic analysis of a novel nontoxigenic Corynebacterium diphtheriae strain isolated from a cancer patient. New Microbes and New Infections, 30. https://dx.doi.org/10.1016/j.nmni.2019.100544

MLA:
Ramdhan, N. D., et al. "Genomic analysis of a novel nontoxigenic Corynebacterium diphtheriae strain isolated from a cancer patient." New Microbes and New Infections 30 (2019).

BibTeX: 

Last updated on 2019-10-05 at 09:01