Influence of zinc ions on structure, bioactivity, biocompatibility and antibacterial potential of melt-derived and gel-derived glasses from CaO-SiO2 system

Journal article


Publication Details

Author(s): Wajda A, Goldmann W, Detsch R, Boccaccini AR, Sitarz M
Journal: Journal of Non-Crystalline Solids
Publication year: 2019
Volume: 511
Pages range: 86-99
ISSN: 0022-3093


Abstract

Several different compositions of zinc-containing glasses in the CaO-SiO2 system were obtained by both traditional melting technique and the sol-gel method. The influence of zinc ions addition in the glass composition was evaluated using different spectroscopic methods (FTIR and Si-29 MAS-NMR). It was demonstrated that ZnO has a significant effect on glass structure and, as a consequence, on thermal properties, texture and bioactivity. EDX and ICP data showed that zinc ions reduce glass bioactivity and incorporate in the newly forming HCA layer. Evaluation of the in vitro biocompatibility of the obtained materials was performed by indirect tests using MG-63 osteoblast-like cells. All samples were found to be biocompatible and zinc ions enhanced the cell viability. Antibacterial tests against gram-negative (E. coli) and gram-positive bacteria (S. aureus) were carried out to evaluate the antibacterial potential of the zinc-doped glasses.


FAU Authors / FAU Editors

Boccaccini, Aldo R. Prof. Dr.-Ing.
Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)
Detsch, Rainer Dr.-Ing.
Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)
Goldmann, Wolfgang Prof.
Lehrstuhl für Biophysik


External institutions with authors

University of Science and Technology (AGH) / Akademia Górniczo-Hutnicza


How to cite

APA:
Wajda, A., Goldmann, W., Detsch, R., Boccaccini, A.R., & Sitarz, M. (2019). Influence of zinc ions on structure, bioactivity, biocompatibility and antibacterial potential of melt-derived and gel-derived glasses from CaO-SiO2 system. Journal of Non-Crystalline Solids, 511, 86-99. https://dx.doi.org/10.1016/j.jnoncrysol.2018.12.040

MLA:
Wajda, Aleksandra, et al. "Influence of zinc ions on structure, bioactivity, biocompatibility and antibacterial potential of melt-derived and gel-derived glasses from CaO-SiO2 system." Journal of Non-Crystalline Solids 511 (2019): 86-99.

BibTeX: 

Last updated on 2019-23-04 at 07:53