Age-related MR characteristics in mild malformation of cortical development with oligodendroglial hyperplasia and epilepsy (MOGHE)

Journal article


Publication Details

Author(s): Hartlieb T, Winkler P, Coras R, Pieper T, Holthausen H, Blümcke I, Staudt M, Kudernatsch M
Journal: Epilepsy & Behavior
Publication year: 2019
Volume: 91
Pages range: 68-74
ISSN: 1525-5050
eISSN: 1525-5069


Abstract

Background: Mild malformation of cortical development with oligodendroglial hyperplasia and epilepsy (MOGHE) is a newly described, rare histopathologic entity detected in resected brain tissue of patients with refractory epilepsies. It shows a predominantly frontal localization causing a difficult-to-treat epilepsy with onset usually in early childhood. Histologically, MOGHE is characterized by blurred gray-white-matter boundaries with increased numbers of heterotopic neurons in the subcortical white matter and increased density of oligodendroglia. Little is known, to date, about radiologic features of MOGHE. Here, we report typical and age-related magnetic resonance (MR) characteristics of MOGHE.


FAU Authors / FAU Editors

Blümcke, Ingmar Prof. Dr.
Lehrstuhl für Neuropathologie


External institutions
Paracelsus Medizinische Privatuniversität
Schön Kliniken


How to cite

APA:
Hartlieb, T., Winkler, P., Coras, R., Pieper, T., Holthausen, H., Blümcke, I.,... Kudernatsch, M. (2019). Age-related MR characteristics in mild malformation of cortical development with oligodendroglial hyperplasia and epilepsy (MOGHE). Epilepsy & Behavior, 91, 68-74. https://dx.doi.org/10.1016/j.yebeh.2018.07.009

MLA:
Hartlieb, Till, et al. "Age-related MR characteristics in mild malformation of cortical development with oligodendroglial hyperplasia and epilepsy (MOGHE)." Epilepsy & Behavior 91 (2019): 68-74.

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Last updated on 2019-08-04 at 13:08