Update Breast Cancer 2019 Part 1-Implementation of Study Results of Novel Study Designs in Clinical Practice in Patients with Early Breast Cancer

Beitrag in einer Fachzeitschrift
(Review-Artikel)


Details zur Publikation

Autor(en): Hartkopf AD, Mueller V, Woeckel A, Lux MP, Janni W, Nabieva N, Taran FA, Ettl J, Lueftner D, Belleville E, Schuetz F, Fasching P, Fehm TN, Kolberg HC, Overkamp F, Schneeweiss A, Tesch H
Zeitschrift: Geburtshilfe und Frauenheilkunde
Jahr der Veröffentlichung: 2019
Band: 79
Heftnummer: 3
Seitenbereich: 256-267
ISSN: 0016-5751


Abstract

For many years, small but significant advancements have been made time and again in the prevention and treatment of early breast cancer. The so-called panel gene analyses are becoming more and more important in prevention, since the risk due to the tested genes is better understood and as a result, concepts for integration in health care can be developed. In the adjuvant situation, the first study in the so-called post-neoadjuvant situation was able to demonstrate a clear improvement in the prognosis with an absent pathological complete remission following trastuzumab or pertuzumab + trastuzumab. Additional studies with this post-neoadjuvant therapeutic concept are still being conducted at present. The CDK4/6 inhibitors which had shown a significant improvement in progression-free survival in a metastatic situation are currently being tested in the adjuvant situation in large therapeutic studies. These and other new data for the treatment or prevention of primary breast cancer are presented in this review against the backdrop of current studies.


FAU-Autoren / FAU-Herausgeber

Fasching, Peter PD Dr.
Professur für Translationale Frauenheilkunde und Geburtshilfe
Nabieva, Naiba Dr. med.
Frauenklinik


Autor(en) der externen Einrichtung(en)
Centrum für Hämatologie und Onkologie Bethanien
Charité - Universitätsmedizin Berlin
ClinSol GmbH & Co.KG
Eberhard Karls Universität Tübingen
Marienhospital Bottrop
OncoConsult
Ruprecht-Karls-Universität Heidelberg
Technische Universität München (TUM)
Universitätsklinikum Düsseldorf
Universitätsklinikum Hamburg-Eppendorf
Universitätsklinikum Heidelberg
Universitätsklinikum Ulm
Universitätsklinikum Würzburg


Zitierweisen

APA:
Hartkopf, A.D., Mueller, V., Woeckel, A., Lux, M.P., Janni, W., Nabieva, N.,... Tesch, H. (2019). Update Breast Cancer 2019 Part 1-Implementation of Study Results of Novel Study Designs in Clinical Practice in Patients with Early Breast Cancer. Geburtshilfe und Frauenheilkunde, 79(3), 256-267. https://dx.doi.org/10.1055/a-0842-6614

MLA:
Hartkopf, Andreas D., et al. "Update Breast Cancer 2019 Part 1-Implementation of Study Results of Novel Study Designs in Clinical Practice in Patients with Early Breast Cancer." Geburtshilfe und Frauenheilkunde 79.3 (2019): 256-267.

BibTeX: 

Zuletzt aktualisiert 2019-05-04 um 21:08