Development and Characterization of Bioactive Glass Containing Composite Coatings with Ion Releasing Function for Antibiotic-Free Antibacterial Surgical Sutures

Journal article


Publication Details

Author(s): Ciraldo F, Schnepf K, Goldmann W, Boccaccini AR
Journal: Materials
Publication year: 2019
Volume: 12
Journal issue: 3
ISSN: 1996-1944


Abstract

Resorbable (Vicryl((R)) Plus) sutures were coated with zinc-doped glass (Zn-BG) and silver-doped ordered mesoporous bioactive glass (Ag-MBG) particles by a dip coating technique. A multilayer approach was used to achieve robust coatings. The first coating was a polymeric layer (e.g., PCL or chitosan) and the second one was a composite made of BG particles in a polymer matrix. The coatings were characterized in terms of morphology by scanning electron microscopy (SEM), in vitro bioactivity, and antibacterial properties. Chitosan/Ag-MBG coatings showed the ability to form hydroxyl-carbonate-apatite on their surfaces after immersion in SBF. An antibacterial effect against Gram (+) and Gram (-) bacteria was confirmed, highlighting the potential application of the coated sutures for antibiotic-free approaches.


FAU Authors / FAU Editors

Boccaccini, Aldo R. Prof. Dr.-Ing.
Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)
Ciraldo, Francesca
Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)
Goldmann, Wolfgang Prof.
Lehrstuhl für Biophysik


How to cite

APA:
Ciraldo, F., Schnepf, K., Goldmann, W., & Boccaccini, A.R. (2019). Development and Characterization of Bioactive Glass Containing Composite Coatings with Ion Releasing Function for Antibiotic-Free Antibacterial Surgical Sutures. Materials, 12(3). https://dx.doi.org/10.3390/ma12030423

MLA:
Ciraldo, Francesca, et al. "Development and Characterization of Bioactive Glass Containing Composite Coatings with Ion Releasing Function for Antibiotic-Free Antibacterial Surgical Sutures." Materials 12.3 (2019).

BibTeX: 

Last updated on 2019-26-03 at 10:23