Gout, Hyperuricemia, and Crystal-Associated Disease Network Consensus Statement Regarding Labels and Definitions for Disease Elements in Gout

Bursill D, Taylor WJ, Terkeltaub R, Kuwabara M, Merriman TR, Grainger R, Pineda C, Louthrenoo W, Edwards NL, Andres M, Vargas-Santos AB, Roddy E, Pascart T, Lin CT, Perez-Ruiz F, Tedeschi SK, Kim SC, Harrold LR, Mccarthy G, Kumar N, Chapman P, Tausche AK, Vazquez-Mellado J, Gutierrez M, Castelar-Pinheiro GDR, Richette P, Pascual E, Fisher MC, Burgos-Vargas R, Robinson PC, Singh JA, Jansen TL, Saag KG, Slot O, Uhlig T, Solomon DH, Keenan RT, Scire CA, Biernat-Kaluza E, Dehlin M, Nuki G, Schlesinger N, Janssen M, Stamp LK, Sivera F, Reginato AM, Jacobsson L, Liote F, Ea HK, Rosenthal A, Bardin T, Choi HK, Hershfield MS, Czegley C, Choi SJ, Dalbeth N (2019)


Publication Type: Journal article

Publication year: 2019

Journal

Book Volume: 71

Pages Range: 427-434

Journal Issue: 3

DOI: 10.1002/acr.23607

Abstract

Objective The language currently used to describe gout lacks standardization. The aim of this project was to develop a consensus statement on the labels and definitions used to describe the basic disease elements of gout. Methods Experts in gout (n = 130) were invited to participate in a Delphi exercise and face-to-face consensus meeting to reach consensus on the labeling and definitions for the basic disease elements of gout. Disease elements and labels in current use were derived from a content analysis of the contemporary medical literature, and the results of this analysis were used for item selection in the Delphi exercise and face-to-face consensus meeting. Results There were 51 respondents to the Delphi exercise and 30 attendees at the face-to-face meeting. Consensus agreement (>= 80%) was achieved for the labels of 8 disease elements through the Delphi exercise; the remaining 3 labels reached consensus agreement through the face-to-face consensus meeting. The agreed labels were monosodium urate crystals, urate, hyperuric(a)emia, tophus, subcutaneous tophus, gout flare, intercritical gout, chronic gouty arthritis, imaging evidence of monosodium urate crystal deposition, gouty bone erosion, and podagra. Participants at the face-to-face meeting achieved consensus agreement for the definitions of all 11 elements and a recommendation that the label "chronic gout" should not be used. Conclusion Consensus agreement was achieved for the labels and definitions of 11 elements representing the fundamental components of gout etiology, pathophysiology, and clinical presentation. The Gout, Hyperuricemia, and Crystal-Associated Disease Network recommends the use of these labels when describing the basic disease elements of gout.

Additional Organisation(s)

Involved external institutions

Hospital General de México MX Mexico (MX) Rio de Janeiro State University / Universidade do Estado do Rio de Janeiro (UERJ) BR Brazil (BR) Assistance Publique-Hôpitaux de Paris (AP-HP) FR France (FR) University of Auckland NZ New Zealand (NZ) Henry Ford Health System (HFHS) US United States (USA) (US) Mater Misericordiae University Hospital (MMUH) / Ospidéal an Mater Misercordiae IE Ireland (IE) University of Gothenburg / Göteborgs universitet SE Sweden (SE) Harvard University US United States (USA) (US) University of Otago NZ New Zealand (NZ) Duke University US United States (USA) (US) University of Basque Country / Universidad del Pais Vasco (UPV) / Euskal Herriko Unibersitatea (EHU) ES Spain (ES) Chiang Mai University (CMU) / มหาวิทยาลัยเชียงใหม่ TH Thailand (TH) Taichung Veterans General Hospital TW Taiwan (TW) Veterans Affairs Medical Center Kansas City US United States (USA) (US) Hospital General Universitario de Alicante ES Spain (ES) University of Florida US United States (USA) (US) Université Catholique de Lille FR France (FR) Glostrup Hospital DK Denmark (DK) Toranomon Hospital JP Japan (JP) Diakonhjemmet Hospital NO Norway (NO) University of Queensland AU Australia (AU) Brown University US United States (USA) (US) Corrona, LLC US United States (USA) (US) International Osteoporosis Foundation (IOF) CH Switzerland (CH) Technische Universität Dresden DE Germany (DE) The State University of New Jersey (Rutgers) US United States (USA) (US) University of Edinburgh GB United Kingdom (GB) Medical College of Wisconsin (MCW) US United States (USA) (US) VieCuri Medisch Centrum / VieCuri Medical Center NL Netherlands (NL) Christchurch Hospital NZ New Zealand (NZ) University of Keele GB United Kingdom (GB) University of Alabama at Birmingham (UAB) US United States (USA) (US) Przychodnia Orlik PL Poland (PL) University of California, San Diego US United States (USA) (US) Università degli Studi di Ferrara IT Italy (IT)

How to cite

APA:

Bursill, D., Taylor, W.J., Terkeltaub, R., Kuwabara, M., Merriman, T.R., Grainger, R.,... Dalbeth, N. (2019). Gout, Hyperuricemia, and Crystal-Associated Disease Network Consensus Statement Regarding Labels and Definitions for Disease Elements in Gout. Arthritis & Rheumatism-Arthritis Care & Research, 71(3), 427-434. https://dx.doi.org/10.1002/acr.23607

MLA:

Bursill, David, et al. "Gout, Hyperuricemia, and Crystal-Associated Disease Network Consensus Statement Regarding Labels and Definitions for Disease Elements in Gout." Arthritis & Rheumatism-Arthritis Care & Research 71.3 (2019): 427-434.

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