Effect of Trinucleotide Repeat Expansion on the Expression of TCF4 mRNA in Fuchs' Endothelial Corneal Dystrophy

Journal article


Publication Details

Author(s): Okumura N, Hayashi R, Nakano M, Yoshii K, Tashiro K, Sato T, Blake DJ, Aleff R, Butz M, Highsmith EW, Wieben ED, Fautsch MP, Baratz KH, Komori Y, Nakahara M, Tourtas T, Schlötzer-Schrehardt U, Kruse F, Koizumi N
Journal: Investigative Ophthalmology & Visual Science
Publication year: 2019
Volume: 60
Journal issue: 2
Pages range: 779-786
ISSN: 0146-0404


Abstract

PURPOSE. CTG trinucleotide repeat (TNR) expansion is frequently found in transcription factor 4 (TCF4) in Fuchs' endothelial corneal dystrophy (FECD), though the effect of TNR expansion on FECD pathophysiology remains unclear. The purpose of this study was to evaluate the effect of TNR expansion on TCF4 expression in corneal endothelium of patients with FECD.


FAU Authors / FAU Editors

Kruse, Friedrich Prof. Dr.
Lehrstuhl für Augenheilkunde
Schlötzer-Schrehardt, Ursula apl. Prof. Dr.
Medizinische Fakultät


External institutions with authors

Cardiff University
Doshisha University / 同志社大学
Kyoto Prefectural University of Medicine / 京都府立医科大学
Mayo Clinic


How to cite

APA:
Okumura, N., Hayashi, R., Nakano, M., Yoshii, K., Tashiro, K., Sato, T.,... Koizumi, N. (2019). Effect of Trinucleotide Repeat Expansion on the Expression of TCF4 mRNA in Fuchs' Endothelial Corneal Dystrophy. Investigative Ophthalmology & Visual Science, 60(2), 779-786. https://dx.doi.org/10.1167/iovs.18-25760

MLA:
Okumura, Naoki, et al. "Effect of Trinucleotide Repeat Expansion on the Expression of TCF4 mRNA in Fuchs' Endothelial Corneal Dystrophy." Investigative Ophthalmology & Visual Science 60.2 (2019): 779-786.

BibTeX: 

Last updated on 2019-15-03 at 12:53