Pitfalls in the measurement of muscle mass: a need for a reference standard

Journal article


Publication Details

Author(s): Buckinx F, Landi F, Cesari M, Fielding RA, Visser M, Engelke K, Maggi S, Dennison E, Al-Daghri NM, Allepaerts S, Bauer J, Bautmans I, Brandi ML, Bruyere O, Cederholm T, Cerreta F, Cherubini A, Cooper C, Cruz-Jentoft A, Mccloskey E, Dawson-Hughes B, Kaufman JM, Laslop A, Petermans J, Reginster JY, Rizzoli R, Robinson S, Rolland Y, Rueda R, Vellas B, Kanis JA
Journal: Journal of Cachexia, Sarcopenia and Muscle
Publication year: 2018
Volume: 9
Journal issue: 2
Pages range: 269-278
ISSN: 2190-5991
eISSN: 2190-6009


Abstract

BACKGROUND: All proposed definitions of sarcopenia include the measurement of muscle mass, but the techniques and threshold values used vary. Indeed, the literature does not establish consensus on the best technique for measuring lean body mass. Thus, the objective measurement of sarcopenia is hampered by limitations intrinsic to assessment tools. The aim of this study was to review the methods to assess muscle mass and to reach consensus on the development of a reference standard.
METHODS: Literature reviews were performed by members of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis working group on frailty and sarcopenia. Face-to-face meetings were organized for the whole group to make amendments and discuss further recommendations.
RESULTS: A wide range of techniques can be used to assess muscle mass. Cost, availability, and ease of use can determine whether the techniques are better suited to clinical practice or are more useful for research. No one technique subserves all requirements but dual energy X-ray absorptiometry could be considered as a reference standard (but not a gold standard) for measuring muscle lean body mass.
CONCLUSIONS: Based on the feasibility, accuracy, safety, and low cost, dual energy X-ray absorptiometry can be considered as the reference standard for measuring muscle mass.


FAU Authors / FAU Editors

Engelke, Klaus Prof. Dr.
Lehrstuhl für Medizinische Physik


External institutions with authors

Abbott Nutrition Research & Development (ANRD)
Carl von Ossietzky Universität Oldenburg
Catholic University of the Sacred Heart / Università Cattolica del Sacro Cuore
Centre Hospitalier Universitaire (CHU) de Toulouse
Centre Hospitalier Universitaire de Liège (CHU Liège)
Consiglio Nazionale delle Ricerche (CNR)
Geneva University Hospitals / Hôpitaux universitaires de Genève (HUG)
Hospital Universitario Ramón y Cajal
Istituto Nazionale di Riposo e Cura per Anziani (IRCCS INRCA)
King Saud University (KSU) / جامعة الملك سعود‎‎
Österreichische Agentur für Gesundheit und Ernährungssicherheit (AGES)
Tufts University
Università degli Studi di Firenze / University of Florence
University Hospital Ghent
University of Liège (ULg) / Université de Liège
University of Sheffield
University of Southampton
Vrije Universiteit Amsterdam (VU) / University Amsterdam
Vrije Universiteit Brussel


How to cite

APA:
Buckinx, F., Landi, F., Cesari, M., Fielding, R.A., Visser, M., Engelke, K.,... Kanis, J.A. (2018). Pitfalls in the measurement of muscle mass: a need for a reference standard. Journal of Cachexia, Sarcopenia and Muscle, 9(2), 269-278. https://dx.doi.org/10.1002/jcsm.12268

MLA:
Buckinx, Fanny, et al. "Pitfalls in the measurement of muscle mass: a need for a reference standard." Journal of Cachexia, Sarcopenia and Muscle 9.2 (2018): 269-278.

BibTeX: 

Last updated on 2019-20-03 at 13:23