Fertility protection: complications of surgery and results of removal and transplantation of ovarian tissue

Journal article

Publication Details

Author(s): Beckmann M, Dittrich R, Lotz L, Van Der Ven K, Van Der Ven HH, Liebenthron J, Korell M, Frambach T, Suetterlin M, Schwab R, Seitz S, Mueller A, Von Wolff M, Haeberlin F, Henes M, Winkler-Crepaz K, Kruessel JS, Germeyer A, Toth B
Journal: Reproductive Biomedicine Online
Publication year: 2018
Volume: 36
Journal issue: 2
Pages range: 188-196
ISSN: 1472-6483


Fertility-preserving measures are becoming important for patients receiving oncological treatment. One method involves cryopreservation of ovarian tissue and transplanting it when treatment is completed. We report complications resulting from surgical and fertility medicine, and the results of procedures for the removal and transplantation of ovarian tissue carried out within the FertiProtekt network. A survey using a structured questionnaire was conducted among the FertiProtekt network centres between November 2015 and June 2016. The analysis included surgical techniques used to remove and transplant ovarian tissue, surgical complications and results. Laparoscopic removal and transplantation of ovarian tissue have a low risk of complications. Surgical complications occurred in three of the network's 1373 ovarian tissue removals (n = 1302) and transplantations (n = 71); two complications (0.2%) occurred during removal and one during transplantation. Menstruation resumed in 47 out of 58 women (81%) who underwent ovarian tissue transplantation. Hormonal activity occurred in 63.2% of transplantations with a follow-up of 6 months or over. Sixteen pregnancies occurred in 14 patients, with nine births. The risks and complications of removal and transplantation of ovarian tissue are similar to those of standard laparoscopy. These procedures are becoming standard for fertility protection in cancer patients.

FAU Authors / FAU Editors

Beckmann, Matthias Prof. Dr.
Lehrstuhl für Geburtshilfe und Frauenheilkunde
Dittrich, Ralf Prof. Dr.
Professur für Experimentelle Reproduktionsmedizin
Lotz, Laura
Professur für Experimentelle Reproduktionsmedizin

External institutions with authors

Albert-Ludwigs-Universität Freiburg
Eberhard Karls Universität Tübingen
Heinrich-Heine-Universität Düsseldorf
Inselspital, Universitätsspital Bern
Johanna-Etienne-Krankenhaus gGmbH
Kantonsspital St.Gallen
Krankenhaus St. Joseph-Stift GmbH
Leopold-Franzens-Universität Innsbruck / University of Innsbruck
Rheinische Friedrich-Wilhelms-Universität Bonn
Ruprecht-Karls-Universität Heidelberg
Städtisches Klinikum Karlsruhe
Universität Regensburg

How to cite

Beckmann, M., Dittrich, R., Lotz, L., Van Der Ven, K., Van Der Ven, H.H., Liebenthron, J.,... Toth, B. (2018). Fertility protection: complications of surgery and results of removal and transplantation of ovarian tissue. Reproductive Biomedicine Online, 36(2), 188-196. https://dx.doi.org/10.1016/j.rbmo.2017.10.109

Beckmann, Matthias, et al. "Fertility protection: complications of surgery and results of removal and transplantation of ovarian tissue." Reproductive Biomedicine Online 36.2 (2018): 188-196.


Last updated on 2019-28-03 at 16:08