Seuß H, Dankerl P, Uder M, Hammon M, Cavallaro AJ (2016)
Publication Type: Journal article
Publication year: 2016
Book Volume: 16
Pages Range: 39
Journal Issue: 1
DOI: 10.1186/s12880-016-0141-0
To evaluate screening and diagnostic accuracy for the detection of osteoblastic rib lesions using an advanced post-processing package enabling in-plane rib reading in CT-images.We retrospectively assessed the CT-data of 60 consecutive prostate cancer patients by applying dedicated software enabling in-plane rib reading. Reading the conventional multiplanar reconstructions was considered to be the reference standard. To simulate clinical practice, the reader was given 10 s to screen for sclerotic rib lesions in each patient applying both approaches. Afterwards, every rib was evaluated individually with both approaches without a time limit. Sensitivities, specificities, positive/negative predictive values and the time needed for detection were calculated depending on the lesion's size (largest diameter < 5 mm, 5-10 mm, > 10 mm).In 53 of 60 patients, all ribs were properly displayed in plane, in five patients ribs were partially displayed correctly, and in two patients none of the ribs were displayed correctly. During the 10-s screening approach all patients with sclerotic rib lesions were correctly identified reading the in-plane images (including the patients without a correct rib segmentation), whereas 14 of 23 patients were correctly identified reading conventional multiplanar images. Overall screening sensitivity, specificity, and positive/negative predictive values were 100/27.0/46.0/100 %, respectively, for in-plane reading and 60.9/100/100/80.4 %, respectively, for multiplanar reading. Overall diagnostic (no time limit) sensitivity, specificity, and positive/negative predictive values of in-plane reading were 97.8/92.8/74.6/99.5 %, respectively. False positive results predominantly occurred for lesions <5 mm in size.In-plane reading of the ribs allows reliable detection of osteoblastic lesions for screening purposes. The limited specificity results from false positives predominantly occurring for small lesions.
APA:
Seuß, H., Dankerl, P., Uder, M., Hammon, M., & Cavallaro, A.J. (2016). Osteoblastic lesion screening with an advanced post-processing package enabling in-plane rib reading in CT-images. BMC Medical Imaging, 16(1), 39. https://doi.org/10.1186/s12880-016-0141-0
MLA:
Seuß, Hannes, et al. "Osteoblastic lesion screening with an advanced post-processing package enabling in-plane rib reading in CT-images." BMC Medical Imaging 16.1 (2016): 39.
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