Indolylvinyl Ketones: Building Blocks for the Synthesis of Natural Products and Bioactive Compounds

Beitrag in einer Fachzeitschrift
(Review-Artikel)


Details zur Publikation

Autor(en): Trushkov IV, Uchuskin MG, Abaev VT, Serdyuk O
Zeitschrift: Synthesis-Stuttgart
Jahr der Veröffentlichung: 2019
Band: 51
Heftnummer: 4
Seitenbereich: 787-815
ISSN: 0039-7881


Abstract

Indolylvinyl ketones are valuable building blocks that can be utilized for the synthesis of numerous natural products and bioactive molecules containing an indole core motif. Herein, we describe their application for the total synthesis of some alkaloids, their analogues, and a variety of other important compounds, with an emphasis on biologically active examples. 1Introduction 2 Functionalization of the Enone C=C Bond 2.1 Reduction 2.2 Michael Addition 2.3 Cycloaddition 3 Transformation of the Carbonyl Group 3.1 Reduction 3.2 Knoevenagel Reaction 3.3 Addition of Organometallic Compounds 3.4 Olefination 4 Reactions Involving the Enone Conjugate System C=C-C=? 4.1 Reactions with 1,2-Dinucleophiles 4.2 Reactions with Compounds Bearing an Active Methylene Group 4.3 Reactions with 1,3-Dinucleophiles 4.4 Reactions with 1,4-Dinucleophiles


FAU-Autoren / FAU-Herausgeber

Serdyuk, Olga Dr.
Lehrstuhl für Pharmazeutische Chemie


Autor(en) der externen Einrichtung(en)
North Ossetian State University
Perm State National Research University / Пермский государственный национальный исследовательский университет
Russian Academy of Sciences / Росси́йская акаде́мия нау́к (RAS)


Zitierweisen

APA:
Trushkov, I.V., Uchuskin, M.G., Abaev, V.T., & Serdyuk, O. (2019). Indolylvinyl Ketones: Building Blocks for the Synthesis of Natural Products and Bioactive Compounds. Synthesis-Stuttgart, 51(4), 787-815. https://dx.doi.org/10.1055/s-0037-1611702

MLA:
Trushkov, Igor V., et al. "Indolylvinyl Ketones: Building Blocks for the Synthesis of Natural Products and Bioactive Compounds." Synthesis-Stuttgart 51.4 (2019): 787-815.

BibTeX: 

Zuletzt aktualisiert 2019-12-03 um 03:08