Indolylvinyl Ketones: Building Blocks for the Synthesis of Natural Products and Bioactive Compounds

Journal article
(Review article)


Publication Details

Author(s): Trushkov IV, Uchuskin MG, Abaev VT, Serdyuk O
Journal: Synthesis-Stuttgart
Publication year: 2019
Volume: 51
Journal issue: 4
Pages range: 787-815
ISSN: 0039-7881


Abstract

Indolylvinyl ketones are valuable building blocks that can be utilized for the synthesis of numerous natural products and bioactive molecules containing an indole core motif. Herein, we describe their application for the total synthesis of some alkaloids, their analogues, and a variety of other important compounds, with an emphasis on biologically active examples. 1Introduction 2 Functionalization of the Enone C=C Bond 2.1 Reduction 2.2 Michael Addition 2.3 Cycloaddition 3 Transformation of the Carbonyl Group 3.1 Reduction 3.2 Knoevenagel Reaction 3.3 Addition of Organometallic Compounds 3.4 Olefination 4 Reactions Involving the Enone Conjugate System C=C-C=? 4.1 Reactions with 1,2-Dinucleophiles 4.2 Reactions with Compounds Bearing an Active Methylene Group 4.3 Reactions with 1,3-Dinucleophiles 4.4 Reactions with 1,4-Dinucleophiles


FAU Authors / FAU Editors

Serdyuk, Olga Dr.
Lehrstuhl für Pharmazeutische Chemie


External institutions with authors

North Ossetian State University
Perm State National Research University / Пермский государственный национальный исследовательский университет
Russian Academy of Sciences / Росси́йская акаде́мия нау́к (RAS)


How to cite

APA:
Trushkov, I.V., Uchuskin, M.G., Abaev, V.T., & Serdyuk, O. (2019). Indolylvinyl Ketones: Building Blocks for the Synthesis of Natural Products and Bioactive Compounds. Synthesis-Stuttgart, 51(4), 787-815. https://dx.doi.org/10.1055/s-0037-1611702

MLA:
Trushkov, Igor V., et al. "Indolylvinyl Ketones: Building Blocks for the Synthesis of Natural Products and Bioactive Compounds." Synthesis-Stuttgart 51.4 (2019): 787-815.

BibTeX: 

Last updated on 2019-12-03 at 03:08