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Indolylvinyl Ketones: Building Blocks for the Synthesis of Natural Products and Bioactive Compounds

Trushkov IV, Uchuskin MG, Abaev VT, Serdyuk O (2019)

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Publication Type: Journal article, Review article

Publication year: 2019

Journal

Book Volume: 51

Pages Range: 787-815

Journal Issue: 4

DOI: 10.1055/s-0037-1611702

Abstract

Indolylvinyl ketones are valuable building blocks that can be utilized for the synthesis of numerous natural products and bioactive molecules containing an indole core motif. Herein, we describe their application for the total synthesis of some alkaloids, their analogues, and a variety of other important compounds, with an emphasis on biologically active examples. 1Introduction 2 Functionalization of the Enone C=C Bond 2.1 Reduction 2.2 Michael Addition 2.3 Cycloaddition 3 Transformation of the Carbonyl Group 3.1 Reduction 3.2 Knoevenagel Reaction 3.3 Addition of Organometallic Compounds 3.4 Olefination 4 Reactions Involving the Enone Conjugate System C=C-C=? 4.1 Reactions with 1,2-Dinucleophiles 4.2 Reactions with Compounds Bearing an Active Methylene Group 4.3 Reactions with 1,3-Dinucleophiles 4.4 Reactions with 1,4-Dinucleophiles

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How to cite

APA:

Trushkov, I.V., Uchuskin, M.G., Abaev, V.T., & Serdyuk, O. (2019). Indolylvinyl Ketones: Building Blocks for the Synthesis of Natural Products and Bioactive Compounds. Synthesis-Stuttgart, 51(4), 787-815. https://dx.doi.org/10.1055/s-0037-1611702

MLA:

Trushkov, Igor V., et al. "Indolylvinyl Ketones: Building Blocks for the Synthesis of Natural Products and Bioactive Compounds." Synthesis-Stuttgart 51.4 (2019): 787-815.

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