Pilot study using intraoperative fluorescence angiography during arteriovenous hemodialysis access surgery

Journal article


Publication Details

Author(s): Regus S, Klingler F, Lang W, Meyer A, Almási-Sperling V, May M, Wüst W, Rother U
Journal: Journal of Vascular Access
Publication year: 2019
Volume: 20
Journal issue: 2
Pages range: 175-183
ISSN: 1129-7298


Abstract

Introduction: In this pilot study, we used indocyanine green fluorescence angiography during hemodialysis access surgery. The aim was to evaluate its relevance as a diagnostic tool to visualize changes in hand microperfusion. Patients and methods: In this prospective single-center study, 47 adult patients (33 male, 14 female) with renal disease (24 preemptive, 23 endstage) were enrolled. Surgical creation of an arteriovenous fistula was performed (22 forearm, 25 upper arm). Microperfusion of the ipsilateral hand and fingers was evaluated intraoperatively using indocyanine green fluorescence angiography. We compared the cumulated microperfusion parameters ingress (In) and ingress rate (InR) before and after opening of the anastomosis. To compare the dimension of microcirculatory decline, we calculated the ratios of the parameters (RatioIn and RatioInR) after to those before anastomosis opening. Results: The cumulated microperfusion parameters In and InR showed a significant decrease after completion of anastomosis and declamping. This effect has been seen in all patients for the hand and for each finger consecutively. During follow-up (mean 4.6, range 3-11 months), 5 patients (10.6%) complained about hemodialysis access-induced distal ischemia. The ratio of intraoperative microperfusion in those five hemodialysis access-induced ischemia patients was significantly lower compared to asymptomatic patients (RatioIn 0.23 vs 0.58, p = 0.001, and RatioInR 0.25 vs 0.62, p = 0.003). Conclusion: Intraoperative fluorescence angiography could visualize the deterioration of ipsilateral hand microperfusion after surgical creation of an arteriovenous fistula. It seems to be a promising tool to detect patients at risk for hemodialysis access-induced distal ischemia early in the peri- or even intraoperative stage.


FAU Authors / FAU Editors

Almási-Sperling, Veronika
Medizinische Fakultät
Lang, Werner apl. Prof. Dr.
Gefäßchirurgische Abteilung
May, Matthias PD Dr.
Radiologisches Institut
Regus, Susanne PD Dr.
Gefäßchirurgische Abteilung
Rother, Ulrich Dr. med.
Professur für Plastische Chirurgie und Handchirurgie
Wüst, Wolfgang PD Dr.
Medizinische Fakultät


How to cite

APA:
Regus, S., Klingler, F., Lang, W., Meyer, A., Almási-Sperling, V., May, M.,... Rother, U. (2019). Pilot study using intraoperative fluorescence angiography during arteriovenous hemodialysis access surgery. Journal of Vascular Access, 20(2), 175-183. https://dx.doi.org/10.1177/1129729818791989

MLA:
Regus, Susanne, et al. "Pilot study using intraoperative fluorescence angiography during arteriovenous hemodialysis access surgery." Journal of Vascular Access 20.2 (2019): 175-183.

BibTeX: 

Last updated on 2019-06-03 at 16:23