Motion artifacts, lesion type, and parenchymal enhancement in breast MRI: what does really influence diagnostic accuracy?

Journal article


Publication Details

Author(s): Clauser P, Dietzel M, Weber M, Kaiser CG, Baltzer PAT
Journal: Acta Radiologica
Publication year: 2019
Volume: 60
Journal issue: 1
Pages range: 19-27
ISSN: 0284-1851


Abstract

BACKGROUND: Motion artifacts can reduce image quality of breast magnetic resonance imaging (MRI). There is a lack of data regarding their effect on diagnostic estimates.
PURPOSE: To evaluate factors that potentially influence readers' diagnostic estimates in breast MRI: motion artifacts; amount of fibroglandular tissue; background parenchymal enhancement; lesion size; and lesion type.
MATERIAL AND METHODS: This Institutional Review Board-approved, retrospective, cross-sectional, single-center study included 320 patients (mean age = 55.1 years) with 334 histologically verified breast lesions (139 benign, 195 malignant) who underwent breast MRI. Two expert breast radiologists evaluated the images considering: motion artifacts (1 = minimal to 4 = marked); fibroglandular tissue (BI-RADS FGT); background parenchymal enhancement (BI-RADS BPE); lesion size; lesion type; and BI-RADS score. Univariate (Chi-square) and multivariate (Generalized Estimation Equations [GEE]) statistics were used to identify factors influencing sensitivity, specificity, and accuracy.
RESULTS: Lesions were: 230 mass (68.9%) and 59 non-mass (17.7%), no foci. Forty-five lesions (13.5%) did not enhance in MRI but were suspicious or unclear in conventional imaging. Sensitivity, specificity, and accuracy were 93.8%, 83.4%, and 89.8% for Reader 1 and 95.4%, 87.8%, and 91.9% for Reader 2. Lower sensitivity was observed in case of increased motion artifacts ( P = 0.007), non-mass lesions ( P < 0.001), and small lesions ≤ 10 mm ( P < 0.021). No further factors (e.g. BPE, FGT) significantly influenced diagnostic estimates. At multivariate analysis, lesion type and size were retained as independent factors influencing the diagnostic performance ( P < 0.033).
CONCLUSION: Motion artifacts can impair lesion characterization with breast MRI, but lesion type and small size have the strongest influence on diagnostic estimates.


FAU Authors / FAU Editors

Dietzel, Matthias Prof. Dr.
Radiologisches Institut


External institutions with authors

Medizinische Universität Wien
Ruprecht-Karls-Universität Heidelberg


How to cite

APA:
Clauser, P., Dietzel, M., Weber, M., Kaiser, C.G., & Baltzer, P.A.T. (2019). Motion artifacts, lesion type, and parenchymal enhancement in breast MRI: what does really influence diagnostic accuracy? Acta Radiologica, 60(1), 19-27. https://dx.doi.org/10.1177/0284185118770918

MLA:
Clauser, Paola, et al. "Motion artifacts, lesion type, and parenchymal enhancement in breast MRI: what does really influence diagnostic accuracy?" Acta Radiologica 60.1 (2019): 19-27.

BibTeX: 

Last updated on 2019-06-03 at 11:38