Interdisciplinary Screening, Diagnosis, Therapy and Follow-up of Breast Cancer. Guideline of the DGGG and the DKG (S3-Level, AWMF Registry Number 032/045OL, December 2017) - Part 2 with Recommendations for the Therapy of Primary, Recurrent and Advanced Breast Cancer

Woeckel A, Festl J, Stueber T, Brust K, Krockenberger M, Heuschmann PU, Jiru-Hillmann S, Albert US, Budach W, Follmann M, Janni W, Kopp I, Kreienberg R, Kuehn T, Langer T, Nothacker M, Scharl A, Schreer I, Link H, Engel J, Fehm T, Weis J, Welt A, Steckelberg A, Feyer P, Koenig K, Hahne A, Baumgartner T, Kreipe HH, Knoefel WT, Denkinger M, Brucker S, Lueftner D, Kubisch C, Gerlach C, Lebeau A, Siedentopf F, Petersen C, Bartsch HH, Schulz-Wendtland R, Hahn M, Hanf V, Mueller-Schimpfle M, Henscher U, Roncarati R, Katalinic A, Heitmann C, Honegger C, Paradies K, Bjelic-Radisic V, Degenhardt F, Wenz F, Rick O, Hoelzel D, Zaiss M, Kemper G, Budach V, Denkert C, Gerber B, Tesch H, Hirsmueller S, Sinn HP, Dunst J, Muenstedt K, Bick U, Fallenberg E, Tholen R, Hung R, Baumann F, Beckmann M, Blohmer J, Fasching P, Lux MP, Harbeck N, Hadji P, Hauner H, Heywang-Koebrunner S, Huober J, Huebner J, Jackisch C, Loibl S, Lueck HJ, Von Minckwitz G, Moebus V, Mueller V, Noethlings U, Schmidt M, Schmutzler R, Schneeweiss A, Schuetz F, Stickeler E, Thomssen C, Untch M, Wesselmann S, Buecker A, Buck A, Stangl S (2018)

Publication Type: Journal article

Publication year: 2018

Journal

Book Volume: 78

Pages Range: 1056-1088

Journal Issue: 11

DOI: 10.1055/a-0646-4630

Abstract

Purpose The aim of this official guideline coordinated and published by the German Society for Gynecology and Obstetrics (DGGG) and the German Cancer Society (DKG) was to optimize the screening, diagnosis, therapy and follow-up care of breast cancer. Method The process of updating the S3 guideline published in 2012 was based on the adaptation of identified source guidelines. They were combined with reviews of evidence compiled using PICO (Patients/Interventions/Control/Outcome) questions and with the results of a systematic search of literature databases followed by the selection and evaluation of the identified literature. The interdisciplinary working groups took the identified materials as their starting point and used them to develop suggestions for recommendations and statements, which were then modified and graded in a structured consensus process procedure. Recommendations Part 2 of this short version of the guideline presents recommendations for the therapy of primary, recurrent and metastatic breast cancer. Loco-regional therapies are de-escalated in the current guideline. In addition to reducing the safety margins for surgical procedures, the guideline also recommends reducing the radicality of axillary surgery. The choice and extent of systemic therapy depends on the respective tumor biology. New substances are becoming available, particularly to treat metastatic breast cancer.

Authors with CRIS profile

Involved external institutions

GBG Forschungs GmbH (German Breast Group) Germany (DE) Universitätsklinikum Düsseldorf Germany (DE) Universitätsklinikum Tübingen Germany (DE) Ludwig-Maximilians-Universität (LMU) Germany (DE) Julius-Maximilians-Universität Würzburg Germany (DE) BRCA-Netzwerk e.V. Germany (DE) Deutscher Verband für Physiotherapie (ZVK) e. V. Germany (DE) Universitätsklinikum Ulm Germany (DE) Universitätsklinikum Hamburg-Eppendorf (UKE) Germany (DE) Frauenselbsthilfe nach Krebs - Bundesverband e. V. Germany (DE) Medizinische Hochschule Hannover (MHH) / Hannover Medical School Germany (DE) Charité - Universitätsmedizin Berlin Germany (DE) Universität Ulm Germany (DE) Universitätsklinikum Schleswig-Holstein (UKSH) Germany (DE) Universitätsklinikum Essen Germany (DE) Centrum für Hämatologie und Onkologie Bethanien Germany (DE) Klinikum St. Marien Amberg Germany (DE) Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen Germany (DE) Universitätsklinikum Freiburg Germany (DE) Evangelisches Krankenhaus Düsseldorf Germany (DE) AWMF-Institut für Medizinisches Wissensmanagement (AWMF-IMWi) Germany (DE) Rheinische Friedrich-Wilhelms-Universität Bonn Germany (DE) Universität des Saarlandes (UdS) Germany (DE) Universitätsklinikum Würzburg Germany (DE) Universitätsklinikum Heidelberg Germany (DE) Universitätsklinikum Jena Germany (DE) HELIOS Kliniken Germany (DE) Universitätsklinikum Köln Germany (DE) Referenzzentrum Mammographie München Germany (DE) Johannes Gutenberg-Universität Mainz (JGU) Germany (DE) Technische Universität München (TUM) Germany (DE) Universitätsklinikum Frankfurt am Main (KGU) Germany (DE) Arbeitskreis Frauengesundheit in Medizin, Psychotherapie und Gesellschaft e. V. (AKF) Germany (DE) Krankenhaus Nordwest Germany (DE) Berufsverband der Frauenärzte e.V. Germany (DE) Klinikum Fürth Germany (DE) Städtische Kliniken Esslingen Germany (DE) Ortenau Klinikum Germany (DE) Albert-Ludwigs-Universität Freiburg Germany (DE) Klinikum Südstadt Rostock Germany (DE) Vivantes - Netzwerk für Gesundheit GmbH Germany (DE) Ruprecht-Karls-Universität Heidelberg Germany (DE) Universitätsklinikum Halle (Saale) Germany (DE) Deutsche Krebsgesellschaft (DKG) Germany (DE) Martin-Luther-Universität Halle-Wittenberg (MLU) Germany (DE) Martin-Luther-Krankenhaus Germany (DE) Sana Klinikum Offenbach Germany (DE) Medizinisches Versorgungszentrum Reinhardshöhe GmbH Germany (DE) Zuger Kantonsspital Switzerland (CH) Universitätsklinikum Mannheim Germany (DE)

How to cite

APA:

Woeckel, A., Festl, J., Stueber, T., Brust, K., Krockenberger, M., Heuschmann, P.U.,... Stangl, S. (2018). Interdisciplinary Screening, Diagnosis, Therapy and Follow-up of Breast Cancer. Guideline of the DGGG and the DKG (S3-Level, AWMF Registry Number 032/045OL, December 2017) - Part 2 with Recommendations for the Therapy of Primary, Recurrent and Advanced Breast Cancer. Geburtshilfe und Frauenheilkunde, 78(11), 1056-1088. https://dx.doi.org/10.1055/a-0646-4630

MLA:

Woeckel, Achim, et al. "Interdisciplinary Screening, Diagnosis, Therapy and Follow-up of Breast Cancer. Guideline of the DGGG and the DKG (S3-Level, AWMF Registry Number 032/045OL, December 2017) - Part 2 with Recommendations for the Therapy of Primary, Recurrent and Advanced Breast Cancer." Geburtshilfe und Frauenheilkunde 78.11 (2018): 1056-1088.

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