Determinants of Incident Malnutrition in Community-Dwelling Older Adults: A MaNuEL Multicohort Meta-Analysis

Streicher M, Van Zwienen J, Bardon L, Nagel G, Teh R, Meisinger C, Colombo M, Torbahn G, Kießwetter E, Flechtner-Mors M, Denkinger M, Rothenbacher D, Thorand B, Ladwig KH, Corish CA, Clarke M, Kerse N, Muru-Lanning M, Gibney ER, Connor EMO, Visser M, Volkert D (2018)

Publication Type: Journal article

Publication year: 2018

Journal

Book Volume: 66

Pages Range: 2335-2343

Journal Issue: 12

DOI: 10.1111/jgs.15553

Abstract

Objectives To identify determinants of incident malnutrition in community-dwelling older adults. Design Meta-analysis of 6 community-based longitudinal datasets with follow-up of 1 to 3 years. SETTING: Datasets from MaNuEL (MalNutrition in the Elderly) partners were included: 3 studies from Germany and 1 each from Ireland, the Netherlands, and New Zealand. Participants community-dwelling adults aged 65 and older (N=4,844). Measurement The same definition of incident malnutrition was used for all cohorts (body mass index<20.0 kg/m(2) at follow-up or weight loss 10 % between baseline and follow-up). Twenty-one potential baseline determinants from 7 domains (demographic, nutritional, lifestyle, social, psychological, physical functioning, medical) and 2 follow-up variables (hospitalization, falls) were harmonized for all studies. Binary logistic regression analyses were performed to assess the association between each variable, adjusted for specific confounders, and incident malnutrition. Combined odds ratios (ORs) with 95% confidence intervals (CIs) were calculated using random-effects meta-analyses. Results Studies included between 209 and 1,841 participants without malnutrition at baseline; mean age ranged from 71.7 to 84.6. Incidence of malnutrition varied from 5.1% and 17.2%. Meta-analyses identified 6 variables as independent determinants of incident malnutrition; with increasing age, the risk of developing malnutrition increased continuously. Unmarried, separated, or divorced participants were more likely to develop malnutrition than married participants, whereas no association was found for widowed participants. Participants with difficulty walking (OR=1.41, 95% CI=1.06-1.89) or difficulty climbing stairs (OR=1.45, 95% CI=1.14-1.85) and those who were hospitalized before baseline (OR=1.49, 95% CI=1.25-1.76) and during follow-up (OR=2.02, 95% CI=1.41-2.88) had higher odds of incident malnutrition. Conclusion In this harmonized meta-analysis based on prospective data of older, community-dwelling adults, age, marital status, limitations with walking and climbing stairs, and hospitalization were identified as determinants of incident malnutrition.

Authors with CRIS profile

Involved external institutions

Vrije Universiteit Amsterdam (VU) / University Amsterdam Netherlands (NL) Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (HMGU) / Helmholtz Munich Germany (DE) University College Dublin (UCD) Ireland (IE) Universität Ulm Germany (DE) University of Auckland New Zealand (NZ) University of Limerick Ireland (IE) Agaplesion Bethesda Klinik Germany (DE)

How to cite

APA:

Streicher, M., Van Zwienen, J., Bardon, L., Nagel, G., Teh, R., Meisinger, C.,... Volkert, D. (2018). Determinants of Incident Malnutrition in Community-Dwelling Older Adults: A MaNuEL Multicohort Meta-Analysis. Journal of the American Geriatrics Society, 66(12), 2335-2343. https://dx.doi.org/10.1111/jgs.15553

MLA:

Streicher, Melanie, et al. "Determinants of Incident Malnutrition in Community-Dwelling Older Adults: A MaNuEL Multicohort Meta-Analysis." Journal of the American Geriatrics Society 66.12 (2018): 2335-2343.

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