Child neurodevelopment and mental health after surgical ventricular septal defect repair: risk and protective factors

Eichler A, Kohler-Jonas N, Stonawski V, Purbojo A, Moll G, Heinrich H, Cesnjevar R, Kratz O (2019)


Publication Type: Journal article

Publication year: 2019

Journal

Book Volume: 61

Pages Range: 152-160

Journal Issue: 2

DOI: 10.1111/dmcn.13992

Abstract

Aim This case-control study examined the long-term consequences of surgical correction for ventricular septal defect (VSD; the most common congenital heart defect) in infancy. It assessed children who had undergone VSD surgery and the factors related to maternal conditions, surgery, and hospital stay. Method Thirty-nine children (23 females, 16 males; age range 6y 1mo-9y 7mo [mean 7y 4mo, SD 1y]) with repaired isolated, non-syndromic, non-genetic VSD were compared with 39 typically developing children (22 females, 17 males; age range 6y-9y 2mo [mean 7y 3mo, SD 10mo]). The children completed behavioural tests of neurodevelopment and a quality of life (QoL) questionnaire. Mothers rated children's emotional/behavioural symptoms and QoL. Measures of maternal parenting behaviour and psychopathology were treated as moderators. Results Affected children showed reduced language skills (p=0.002) unless mothers reported high parenting behaviour subscale scores (p=0.04). Children's anxiety symptoms were elevated when mothers had anxiety symptoms (p=0.01). Longer hospital stay was associated with lower intelligence (p=0.003) and psychomotor scores (p=0.006). Longer scars predicted elevated child anxiety (p=0.008), and age at surgery and QoL were inversely related (p=0.01). Interpretation Impairments could be mitigated if VSD repair was performed early in life with a relatively small scar and uncomplicated hospital stay. This outcome depends on maternal parenting behaviour and anxiety symptoms. What this paper adds

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APA:

Eichler, A., Kohler-Jonas, N., Stonawski, V., Purbojo, A., Moll, G., Heinrich, H.,... Kratz, O. (2019). Child neurodevelopment and mental health after surgical ventricular septal defect repair: risk and protective factors. Developmental Medicine and Child Neurology, 61(2), 152-160. https://doi.org/10.1111/dmcn.13992

MLA:

Eichler, Anna, et al. "Child neurodevelopment and mental health after surgical ventricular septal defect repair: risk and protective factors." Developmental Medicine and Child Neurology 61.2 (2019): 152-160.

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