Non-redundant functions of EMT transcription factors

Journal article


Publication Details

Author(s): Stemmler M, Eccles R, Brabletz S, Brabletz T
Journal: Nature Cell Biology
Publication year: 2019
Volume: 21
Journal issue: 1
Pages range: 102-112
ISSN: 1465-7392


Abstract

Epithelial-mesenchymal transition (EMT) is a crucial embryonic programme that is executed by various EMT transcription factors (EMT-TFs) and is aberrantly activated in cancer and other diseases. However, the causal role of EMT and EMT-TFs in different disease processes, especially cancer and metastasis, continues to be debated. In this Review, we identify and describe specific, non-redundant functions of the different EMT-TFs and discuss the reasons that may underlie disputes about EMT in cancer.


FAU Authors / FAU Editors

Brabletz, Thomas Prof. Dr. med.
Lehrstuhl für Experimentelle Medizin mit dem Schwerpunkt Molekulare Pathogeneseforschung
Brabletz, Simone PD Dr.
Lehrstuhl für Experimentelle Medizin II (Molekulare Tumorforschung)
Eccles, Rebecca
Lehrstuhl für Experimentelle Medizin mit dem Schwerpunkt Molekulare Pathogeneseforschung
Stemmler, Marc PD Dr.
Lehrstuhl für Experimentelle Medizin mit dem Schwerpunkt Molekulare Pathogeneseforschung


How to cite

APA:
Stemmler, M., Eccles, R., Brabletz, S., & Brabletz, T. (2019). Non-redundant functions of EMT transcription factors. Nature Cell Biology, 21(1), 102-112. https://dx.doi.org/10.1038/s41556-018-0196-y

MLA:
Stemmler, Marc, et al. "Non-redundant functions of EMT transcription factors." Nature Cell Biology 21.1 (2019): 102-112.

BibTeX: 

Last updated on 2019-06-02 at 08:38