Non-redundant functions of EMT transcription factors

Stemmler M, Eccles R, Brabletz S, Brabletz T (2019)

Publication Type: Journal article

Publication year: 2019

Journal

Nature Cell Biology Nature Research

Book Volume: 21

Pages Range: 102-112

Journal Issue: 1

DOI: 10.1038/s41556-018-0196-y

Abstract

Epithelial-mesenchymal transition (EMT) is a crucial embryonic programme that is executed by various EMT transcription factors (EMT-TFs) and is aberrantly activated in cancer and other diseases. However, the causal role of EMT and EMT-TFs in different disease processes, especially cancer and metastasis, continues to be debated. In this Review, we identify and describe specific, non-redundant functions of the different EMT-TFs and discuss the reasons that may underlie disputes about EMT in cancer.

Authors with CRIS profile

Marc Stemmler Lehrstuhl für Experimentelle Medizin mit dem Schwerpunkt Molekulare Pathogeneseforschung Rebecca Eccles Lehrstuhl für Experimentelle Medizin mit dem Schwerpunkt Molekulare Pathogeneseforschung Simone Brabletz Lehrstuhl für Experimentelle Medizin II (Molekulare Tumorforschung) Thomas Brabletz Lehrstuhl für Experimentelle Medizin mit dem Schwerpunkt Molekulare Pathogeneseforschung

Additional Organisation(s)

Interdisziplinäres Zentrum für Klinische Forschung

How to cite

APA:

Stemmler, M., Eccles, R., Brabletz, S., & Brabletz, T. (2019). Non-redundant functions of EMT transcription factors. Nature Cell Biology, 21(1), 102-112. https://dx.doi.org/10.1038/s41556-018-0196-y

MLA:

Stemmler, Marc, et al. "Non-redundant functions of EMT transcription factors." Nature Cell Biology 21.1 (2019): 102-112.

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