Ur Rehman MA, Bastan FE, Nawaz Q, Goldmann W, Maqbool M, Virtanen S, Boccaccini AR (2018)
Publication Status: Published
Publication Type: Journal article
Publication year: 2018
Book Volume: 106
Pages Range: 3111-3122
Journal Issue: 12
DOI: 10.1002/jbm.a.36506
In this study, chitosan/bioactive glass (BG)/lawsone coatings were deposited by electrophoretic deposition (EPD) on polyetheretherketone (PEEK)/BG layers (previously deposited by EPD on 316-L stainless steel) to produce bioactive and antibacterial coatings. First, the EPD of chitosan/BG/lawsone was optimized on stainless steel in terms of suspension stability, homogeneity and thickness of coatings. Subsequently, the optimized EPD parameters were used to produce bioresorbable chitosan/bioactive glass (BG)/lawsone coatings on PEEK/BG layers. The produced layered coatings were characterized in terms of composition, microstructure, corrosion resistance, in vitro bioactivity, drug release kinetics and antibacterial activity. Ultraviolet/Visible (UV/VIS) spectroscopic analyses confirmed the release of lawsone from the coatings. Moreover, the deposition of chitosan/BG coatings was confirmed by Scanning Electron Microscopy (SEM) and Fourier Transform Infrared spectroscopy (FTIR). The coated specimens presented higher corrosion resistance (10 times) in comparison to that of bare 316-L stainless steel and showed convenient wettability for initial protein attachment. The presence of lawsone in the top layer provided antibacterial effects against Staphylococcus carnosus. Moreover, the developed coatings formed apatite-like crystals upon immersion in simulated body fluid, indicating the possibility of achieving close interaction between the coating surface and bone. © 2018 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 106A: 3111-3122, 2018.
APA:
Ur Rehman, M.A., Bastan, F.E., Nawaz, Q., Goldmann, W., Maqbool, M., Virtanen, S., & Boccaccini, A.R. (2018). Electrophoretic deposition of lawsone loaded bioactive glass (BG)/chitosan composite on polyetheretherketone (PEEK)/BG layers as antibacterial and bioactive coating. Journal of Biomedical Materials Research Part A, 106(12), 3111-3122. https://doi.org/10.1002/jbm.a.36506
MLA:
Ur Rehman, Muhammad Atiq, et al. "Electrophoretic deposition of lawsone loaded bioactive glass (BG)/chitosan composite on polyetheretherketone (PEEK)/BG layers as antibacterial and bioactive coating." Journal of Biomedical Materials Research Part A 106.12 (2018): 3111-3122.
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