Reakasame S, Trapani D, Detsch R, Boccaccini AR (2018)
Publication Status: Published
Publication Type: Journal article
Publication year: 2018
Book Volume: 29
Pages Range: 185
Journal Issue: 12
DOI: 10.1007/s10856-018-6195-5
Microcapsules based on alginate-keratin, alginate dialdehyde (ADA)-keratin and ADA-keratin-45S5 bioactive glass (BG) were successfully prepared. The samples were characterized by light microscopy, scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR). The results showed that ADA-based materials possess higher degradation rate compared to alginate-based materials. The incorporation of BG particles (mean particle size: 2.0 µm) improved the bioactivity of the materials. Moreover, the biological properties of the samples were evaluated by encapsulating MG-63 osteosarcoma cells into the microcapsules. The cell viability in all samples increased during 21 days of cultivation. However, the presence of 0.5% BG particle seemed to have initial negative effect on cell growth compared to other samples without BG. On the other hand, the positive effect of CaP formation was visible after 3 weeks in the BG containing samples. The results are relevant to consider the development of cell laden bioinks incorporating inorganic bioactive particles for biofabrication approaches.
APA:
Reakasame, S., Trapani, D., Detsch, R., & Boccaccini, A.R. (2018). Cell laden alginate-keratin based composite microcapsules containing bioactive glass for tissue engineering applications. Journal of Materials Science: Materials in Medicine, 29(12), 185. https://dx.doi.org/10.1007/s10856-018-6195-5
MLA:
Reakasame, Supachai, et al. "Cell laden alginate-keratin based composite microcapsules containing bioactive glass for tissue engineering applications." Journal of Materials Science: Materials in Medicine 29.12 (2018): 185.
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