Cell laden alginate-keratin based composite microcapsules containing bioactive glass for tissue engineering applications.

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Details zur Publikation

Autorinnen und Autoren: Reakasame S, Trapani D, Detsch R, Boccaccini AR
Zeitschrift: Journal of Materials Science-Materials in Medicine
Jahr der Veröffentlichung: 2018
Band: 29
Heftnummer: 12
Seitenbereich: 185
ISSN: 0957-4530


Abstract

Microcapsules based on alginate-keratin, alginate dialdehyde (ADA)-keratin and ADA-keratin-45S5 bioactive glass (BG) were successfully prepared. The samples were characterized by light microscopy, scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR). The results showed that ADA-based materials possess higher degradation rate compared to alginate-based materials. The incorporation of BG particles (mean particle size: 2.0 µm) improved the bioactivity of the materials. Moreover, the biological properties of the samples were evaluated by encapsulating MG-63 osteosarcoma cells into the microcapsules. The cell viability in all samples increased during 21 days of cultivation. However, the presence of 0.5% BG particle seemed to have initial negative effect on cell growth compared to other samples without BG. On the other hand, the positive effect of CaP formation was visible after 3 weeks in the BG containing samples. The results are relevant to consider the development of cell laden bioinks incorporating inorganic bioactive particles for biofabrication approaches.


FAU-Autorinnen und Autoren / FAU-Herausgeberinnen und Herausgeber

Boccaccini, Aldo R. Prof. Dr.-Ing.
Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)
Detsch, Rainer Dr.-Ing.
Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)
Reakasame, Supachai
Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)


Zitierweisen

APA:
Reakasame, S., Trapani, D., Detsch, R., & Boccaccini, A.R. (2018). Cell laden alginate-keratin based composite microcapsules containing bioactive glass for tissue engineering applications. Journal of Materials Science-Materials in Medicine, 29(12), 185. https://dx.doi.org/10.1007/s10856-018-6195-5

MLA:
Reakasame, Supachai, et al. "Cell laden alginate-keratin based composite microcapsules containing bioactive glass for tissue engineering applications." Journal of Materials Science-Materials in Medicine 29.12 (2018): 185.

BibTeX: 

Zuletzt aktualisiert 2019-29-01 um 08:38